Evidence map›Paper›PMID 35330924›Full record

ArticleFunction (Oxford, England)2022

Calcium Signaling in the Photodamaged Skin: In Vivo Experiments and Mathematical Modeling.

Viola Donati, Chiara Peres, Chiara Nardin, Ferdinando Scavizzi, Marcello Raspa, Catalin D Ciubotaru, Mario Bortolozzi, Morten Gram Pedersen, Fabio Mammano

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Function (Oxford, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Physical models of embryonic epithelial healing.PLoS computational biology · 2026
    Review
  4. Article
  5. CaEMBO reports · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. A Quantitative Assay for CaInternational journal of molecular sciences · 2022
    Article
  15. Article
  16. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Viola DonatiDepartment of Physics and Astronomy "G. Galilei", University of Padova, 35131 Padova, Italy.
Chiara PeresInstitute of Biochemistry and Cell Biology (IBBC)-CNR, 00015 Monterotondo (RM), Italy.
Chiara NardinInstitute of Biochemistry and Cell Biology (IBBC)-CNR, 00015 Monterotondo (RM), Italy.ORCID 0000-0002-4084-4932
Ferdinando ScavizziInstitute of Biochemistry and Cell Biology (IBBC)-CNR, 00015 Monterotondo (RM), Italy.
Marcello RaspaInstitute of Biochemistry and Cell Biology (IBBC)-CNR, 00015 Monterotondo (RM), Italy.
Catalin D CiubotaruIOM-CNR, Institute of Materials, Area Science, 34149 Basovizza (TS), Italy.
Mario BortolozziDepartment of Physics and Astronomy "G. Galilei", University of Padova, 35131 Padova, Italy.ORCID 0000-0001-7198-9838
Morten Gram PedersenDepartment of Information Engineering, University of Padova, 35131 Padova (PD), Italy.
Fabio MammanoDepartment of Physics and Astronomy "G. Galilei", University of Padova, 35131 Padova, Italy.ORCID 0000-0003-3751-1691
Institute of Cell Biology and Neurobiology · ITUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The epidermis forms an essential barrier against a variety of insults. The overall goal of this study was to shed light not only on the effects of accidental epidermal injury, but also on the mechanisms that support laser skin resurfacing with intra-epidermal focal laser-induced photodamage, a widespread medical practice used to treat a range of skin conditions. To this end, we selectively photodamaged a single keratinocyte with intense, focused and pulsed laser radiation, triggering Ca

Indexed as

CalciumCalcium SignalingAdenosine TriphosphateAnimalsConnexinsMiceSkinAdenosine TriphosphateCalciumConnexinsconnexinslaser-induced intra-epidermal photodamagemathematical modelpannexinspurinergic signalingreaction-diffusion equationsSkinwound healing

Identifiers

PMID35330924
PMCPMC8788836
OpenAlexW4200541530

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.