Evidence map›Paper›PMID 35330821›Full record

ArticleFrontiers in oral health2022

Gingival Transcriptome of Innate Antimicrobial Factors and the Oral Microbiome With Aging and Periodontitis.

Jeffrey L Ebersole, Sreenatha Kirakodu, Linh Nguyen, Octavio A Gonzalez

Abstract read
In one paragraph

Article in Frontiers in oral health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jeffrey L EbersoleDepartment of Biomedical Sciences, School of Dental Medicine, University of Nevada Las Vegas, Las Vegas, NV, United States.
Sreenatha KirakoduCenter for Oral Health Research, College of Dentistry, University of Kentucky, Lexington, KY, United States.
Linh NguyenDepartment of Biomedical Sciences, School of Dental Medicine, University of Nevada Las Vegas, Las Vegas, NV, United States.
Octavio A GonzalezCenter for Oral Health Research, College of Dentistry, University of Kentucky, Lexington, KY, United States.

Funding

Translational Research at the CPRC:genetic model of primate circadian disorderP40RR003640 · NCRR · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI KRAISELBURD, EDMUNDO NELSON · 1987 to 2011
$21.1M
Center for the Biologic Basis of Oral/Systemic Disease (CBBOSD)P20GM103538 · NIGMS · UNIVERSITY OF KENTUCKY · PI EBERSOLE, JEFFREY L · 2012 to 2013
$4.2M
NCRR NIH HHS P40 RR003640NIGMS NIH HHS P20 GM103538
6 · The paper itself

Abstract

The epithelial barrier at mucosal sites comprises an important mechanical protective feature of innate immunity, and is intimately involved in communicating signals of infection/tissue damage to inflammatory and immune cells in these local environments. A wide array of antimicrobial factors (AMF) exist at mucosal sites and in secretions that contribute to this innate immunity. A non-human primate model of ligature-induced periodontitis was used to explore characteristics of the antimicrobial factor transcriptome (

Indexed as

agingantimicrobial factorsmicrobiomenon-human primateperiodontitis

Identifiers

PMID35330821
PMCPMC8940521

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.