Evidence map›Paper›PMID 35330488›Full record

ArticleJournal of personalized medicine2022

Whole Exome Sequencing in Healthy Individuals of Extreme Constitution Types Reveals Differential Disease Risk: A Novel Approach towards Predictive Medicine.

Tahseen Abbas, Gaura Chaturvedi, P Prakrithi, Ankit Kumar Pathak, Rintu Kutum, Pushkar Dakle, Ankita Narang, Vijeta Manchanda, Rutuja Patil, Dhiraj Aggarwal and 9 more

Abstract read
In one paragraph

Article in Journal of personalized medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. A scoping review of clinicalFrontiers in medicine · 2026
    Pooled it
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Tahseen AbbasCentre of Excellence for Applied Development of Ayurveda Prakriti and Genomics, CSIR Ayurgenomics Unit-TRISUTRA, CSIR-Institute of Genomics & Integrative Biology, Delhi 110020, India.
Gaura ChaturvediCentre of Excellence for Applied Development of Ayurveda Prakriti and Genomics, CSIR Ayurgenomics Unit-TRISUTRA, CSIR-Institute of Genomics & Integrative Biology, Delhi 110020, India.ORCID 0000-0003-0369-8486
P PrakrithiGenomics and Molecular Medicine, CSIR-Institute of Genomics & Integrative Biology, Mathura Road, Delhi 110020, India.
Ankit Kumar PathakGenomics and Molecular Medicine, CSIR-Institute of Genomics & Integrative Biology, Mathura Road, Delhi 110020, India.
Rintu KutumCentre of Excellence for Applied Development of Ayurveda Prakriti and Genomics, CSIR Ayurgenomics Unit-TRISUTRA, CSIR-Institute of Genomics & Integrative Biology, Delhi 110020, India.ORCID 0000-0001-8667-6199
Pushkar DakleCentre of Excellence for Applied Development of Ayurveda Prakriti and Genomics, CSIR Ayurgenomics Unit-TRISUTRA, CSIR-Institute of Genomics & Integrative Biology, Delhi 110020, India.
Ankita NarangCentre of Excellence for Applied Development of Ayurveda Prakriti and Genomics, CSIR Ayurgenomics Unit-TRISUTRA, CSIR-Institute of Genomics & Integrative Biology, Delhi 110020, India.
Vijeta ManchandaCentre of Excellence for Applied Development of Ayurveda Prakriti and Genomics, CSIR Ayurgenomics Unit-TRISUTRA, CSIR-Institute of Genomics & Integrative Biology, Delhi 110020, India.
Rutuja PatilVadu Rural Health Program, KEM Hospital Research Centre, Pune 412216, India.ORCID 0000-0001-6390-4363
Dhiraj AggarwalVadu Rural Health Program, KEM Hospital Research Centre, Pune 412216, India.ORCID 0000-0002-7868-9309
Bhushan GiraseVadu Rural Health Program, KEM Hospital Research Centre, Pune 412216, India.ORCID 0000-0001-7105-3730
Ankita SrivastavaVadu Rural Health Program, KEM Hospital Research Centre, Pune 412216, India.
Manav KapoorDepartment of Neuroscience, Icahn School of Medicine at Mt. Sinai, New York, NY 10029, USA.
Ishaan GuptaDepartment of Biochemical Engineering and Biotechnology, Indian Institute of Technology Delhi, New Delhi 110016, India.ORCID 0000-0001-8934-9919
Rajesh PandeyINtegrative GENomics of HOst-PathogEn (INGEN-HOPE) Laboratory, CSIR-Institute of Genomics and Integrative Biology (CSIR-IGIB), Delhi 110007, India.
Sanjay JuvekarVadu Rural Health Program, KEM Hospital Research Centre, Pune 412216, India.ORCID 0000-0002-7209-6924
Debasis DashInformatics and Big Data Unit, CSIR-Institute of Genomics & Integrative Biology, Mathura Road, Delhi 110020, India.
Mitali MukerjiCentre of Excellence for Applied Development of Ayurveda Prakriti and Genomics, CSIR Ayurgenomics Unit-TRISUTRA, CSIR-Institute of Genomics & Integrative Biology, Delhi 110020, India.
Bhavana PrasherCentre of Excellence for Applied Development of Ayurveda Prakriti and Genomics, CSIR Ayurgenomics Unit-TRISUTRA, CSIR-Institute of Genomics & Integrative Biology, Delhi 110020, India.ORCID 0000-0003-4185-4400

Funding

Center of Excellence on Applied Developments in Ayurveda, Prakriti and Genomics, Grant by Ministry of AYUSH GAP-0183Council of Scientific Research (CSIR) TRISUTRA MLP-901
6 · The paper itself

Abstract

Precision medicine aims to move from traditional reactive medicine to a system where risk groups can be identified before the disease occurs. However, phenotypic heterogeneity amongst the diseased and healthy poses a major challenge for identification markers for risk stratification and early actionable interventions. In Ayurveda, individuals are phenotypically stratified into seven constitution types based on multisystem phenotypes termed "

Indexed as

ayurgenomicsdeep phenotypesexomesexome sequencingextreme phenotypesprecision medicinerisk stratification

Identifiers

PMID35330488
PMCPMC8952204

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.