ReviewJournal of personalized medicine2022
Dental and Skeletal Side Effects of Oral Appliances Used for the Treatment of Obstructive Sleep Apnea and Snoring in Adult Patients-A Systematic Review and Meta-Analysis.
Review in Journal of personalized medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Dentoskeletal changes of long-term oral appliance treatment in patients with obstructive sleep apnea: A systematic review and meta-analysis.Journal of prosthodontics : official journal of the American College of Prosthodontists · 2025Pooled it
- Mandibular advancement devices decrease systolic pressure during the day and night in patients with obstructive sleep apnea: A systematic review and meta-analysis.Sleep & breathing = Schlaf & Atmung · 2024Pooled it
- Dental Appliances for the Treatment of Obstructive Sleep Apnea in Children: A Systematic Review and Meta-Analysis.Medicina (Kaunas, Lithuania) · 2023Pooled it
- Trial
- Sensor-derived wearing time predicts 3D orthodontic side effects during mandibular advancement therapy of obstructive sleep apnea.Clinical oral investigations · 2026Article
- Retention vs. Stability: A Comparative Study of Thermoplastic Materials for Oral Appliance Therapy.Cureus · 2026Article
- Treatment choice in mild to moderate sleep apnoea in the European Sleep Apnea Database.ERJ open research · 2025Article
- Changes and Correlations Between the Width and Height of the Hard Palate During Rapid Maxillary Expansion with a Printed Tooth-Borne Expander.Healthcare (Basel, Switzerland) · 2025Article
- Study on Quality of Life of Patients with Obstructive Sleep Apnea-Pilot Study.Medicina (Kaunas, Lithuania) · 2025Article
- Three-dimensional pharyngeal airway and hyoid bone changes in skeletal class I malocclusion treated with extraction and non-extraction protocols: a comparative study of fixed orthodontic appliance and clear aligners.Clinical oral investigations · 2025Article
- A Survey of Physicians' Knowledge and Practices Towards Oral Appliance Therapy for Obstructive Sleep Apnea Treatment.Dentistry journal · 2025Article
- Objectively measured adherence may affect side effects of mandibular advancement therapy in subjects with obstructive sleep apnea.Sleep & breathing = Schlaf & Atmung · 2024Article
- Indications for Dental Specialists for Treating Obstructive Sleep Apnea with Mandibular Advancement Devices: A Narrative Review.International journal of dentistry · 2024Review
- A Multicenter Prospective Study on the Use of a Mandibular Advancement Device in the Treatment of Obstructive Sleep Apnea.Dentistry journal · 2023Article
- Influence of Surgeon Experience on Surgical Outcome of Maxillomandibular Advancement for Obstructive Sleep Apnea.Journal of clinical medicine · 2023Article
- Cutting-Edge Approaches in Respiratory and Critical Care Medicine.Journal of personalized medicine · 2023Article
- Obstructive sleep apnea: a review for the orthodontist.Dental press journal of orthodontics · 2023Review
- Dental and Occlusal Changes during Mandibular Advancement Device Therapy in Japanese Patients with Obstructive Sleep Apnea: Four Years Follow-Up.Journal of clinical medicine · 2022Article
- Artificial Intelligence as an Aid in CBCT Airway Analysis: A Systematic Review.Life (Basel, Switzerland) · 2022Review
- Smartphone-Based Facial Scanning as a Viable Tool for Facially Driven Orthodontics?Sensors (Basel, Switzerland) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMandibular advancement devices for obstructive sleep apnea treatment are becoming increasingly popular among patients who do not prefer CPAP devices or surgery. Our study aims to evaluate the literature regarding potential dental and skeletal side effects caused by mandibular advancement appliances used for adult OSA treatment.
methodsElectronic databases were searched for published and unpublished literature along with the reference lists of the eligible studies. Randomized clinical trials and non-randomized trials assessing dental and skeletal changes by comparing cephalometric radiographs were selected. Study selection, data extraction, and risk of bias assessment were performed individually and in duplicate. Fourteen articles were finally selected (two randomized clinical trials and 12 non-randomized trials).
resultsThe results suggest that mandibular advancement devices used for OSA treatment increase the lower incisor proclination by 1.54 ± 0.16°, decrease overjet by 0.89 ± 0.04 mm and overbite by 0.68 ± 0.04 mm, rotate the mandible downward and forward, and increase the SNA angle by to 0.06 ± 0.03°. The meta-analysis revealed high statistical heterogeneity.
conclusionsThe MADs affect the lower incisor proclination, overjet, overbite, the rotation of the mandible and the SNA angle. More randomized clinical trials providing high-quality evidence are needed to support those findings.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.