Evidence map›Paper›PMID 35330463›Full record

ArticleJournal of personalized medicine2022

The Dissimilar Impact in Atrial Substrate Modificationof Left and Right Pulmonary Veins Isolation after Catheter Ablation of Paroxysmal Atrial Fibrillation.

Aikaterini Vraka, Vicente Bertomeu-González, Lorenzo Fácila, José Moreno-Arribas, Raúl Alcaraz, José J Rieta

Abstract read
In one paragraph

Article in Journal of personalized medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Aikaterini VrakaBioMIT.org, Electronic Engineering Department, Universitat Politecnica de Valencia, 46022 Valencia, Spain.ORCID 0000-0001-5984-904X
Vicente Bertomeu-GonzálezCardiology Department, Saint John's University Hospital, 03550 Alicante, Spain.ORCID 0000-0001-5309-0562
Lorenzo FácilaCardiology Department, General University Hospital Consortium of Valencia, 46014 Valencia, Spain.ORCID 0000-0003-1402-4364
José Moreno-ArribasCardiology Department, Saint John's University Hospital, 03550 Alicante, Spain.ORCID 0000-0002-4070-6476
Raúl AlcarazResearch Group in Electronic, Biomedical and Telecommunication Engineering, University of Castilla-La Mancha, 16071 Cuenca, Spain.ORCID 0000-0002-0942-3638
José J RietaBioMIT.org, Electronic Engineering Department, Universitat Politecnica de Valencia, 46022 Valencia, Spain.ORCID 0000-0002-3364-6380

Funding

European Regional Development Fund (EU) - Spanish Government 10.13039/501100011033Generalitat Valenciana AICO/2021/286Junta de Comunidades Castilla-La Mancha SB-PLY/17/180501/000411Ministry of Economy, Industry and Competitiveness DPI2017-83952-C3Ministry of Economy, Industry and Competitiveness PID2021-00X128525-IV0Ministry of Economy, Industry and Competitiveness PID2021-123804OB-I00Ministry of Economy, Industry and Competitiveness TED2021-129996B-I00
6 · The paper itself

Abstract

Since the discovery of pulmonary veins (PVs) as foci of atrial fibrillation (AF), the commonest cardiac arrhythmia, investigation revolves around PVs catheter ablation (CA) results. Notwithstanding, CA process itself is rather neglected. We aim to decompose crucial CA steps: coronary sinus (CS) catheterization and the impact of left and right PVs isolation (LPVI, RPVI), separately. We recruited 40 paroxysmal AF patients undergoing first-time CA and obtained five-minute lead II and bipolar CS recordings during sinus rhythm (SR) before CA (B), after LPVI (L) and after RPVI (R). Among others, duration, amplitude and atrial-rate variability (ARV) were calculated for P-waves and CS local activation waves (LAWs). LAWs features were compared among CS channels for reliability analysis. P-waves and LAWs features were compared after each ablation step (B, L, R). CS channels: amplitude and area were different between distal/medial (p≤0.0014) and distal/mid-proximal channels (p≤0.0025). Medial and distal showed the most and least coherent values, respectively. Correlation was higher in proximal (≥93%) than distal (≤91%) areas. P-waves: duration was significantly shortened after LPVI (after L: p=0.0012, −13.30%). LAWs: insignificant variations. ARV modification was more prominent in LAWs (L: >+73.12%, p≤0.0480, R: <−33.94%, p≤0.0642). Medial/mid-proximal channels are recommended during SR. CS LAWs are not significantly affected by CA but they describe more precisely CA-induced ARV modifications. LPVI provokes the highest impact in paroxysmal AF CA, significantly modifying P-wave duration.

Indexed as

atrial fibrillationcatheter ablationcatheter channelscoronary sinusheart rate variabilityleft pulmonary veinslocal activation wavesP-waves

Identifiers

PMID35330463
PMCPMC8955667

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.