ArticleJournal of personalized medicine2022
Post-Stroke Depression and Cognitive Aging: A Multicenter, Prospective Cohort Study.
Article in Journal of personalized medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 3 syntheses or guidelines pooled it, 18 citations in OpenAlex.
- Repetitive transcranial magnetic stimulation for treating post-stroke depression: a systematic review and network meta-analysis.BMC psychiatry · 2025Pooled it
- Prevalence and natural history of depression after stroke: A systematic review and meta-analysis of observational studies.PLoS medicine · 2023Pooled it
- Effect of acupuncture combined with antidepressants on post-stroke depression: A network meta-analysis of nine acupuncture therapy.Frontiers in neurology · 2023Pooled it
- Long-Term Effect of Intensive Education in Patients With First-Ever Ischemic Stroke.Journal of the American Heart Association · 2026Article
- Age, race, and education as moderators of post-stroke cognitive decline following dental care.Frontiers in stroke · 2026Article
- Network-based predictive models for artificial intelligence: an interpretable application of machine learning techniques in the assessment of depression in stroke patients.BMC geriatrics · 2025Article
- Post-Stroke Brain Health Monitoring and Optimization: A Narrative Review.Journal of clinical medicine · 2023Review
- The Impact of Post-Stroke Depressive Symptoms on Cognitive Performance in Women and in Men: A 4 Month Prospective Study.Life (Basel, Switzerland) · 2023Article
- The characteristics of brain network in patient with post-stroke depression under cognitive task condition.Frontiers in neuroscience · 2023Article
- What should nurses do on post-stroke depression? A global systematic assessment of clinical practice guidelines.BMJ open · 2022Article
- The enigma of vascular depression in old age: a critical update.Journal of neural transmission (Vienna, Austria : 1996) · 2022Review
- Article
- Association between early depressive symptoms after stroke and trajectories of functional recovery among patients with acute ischemic stroke: a longitudinal study.Frontiers in neurologyArticle
Corrections and comments
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Authors and funding
18 authors at 12 institutions in 1 country.
Funding
Abstract
Background: This study investigated the impact of post-stroke depression (PSD) on cognitive aging in elderly stroke patients. Methods: This study was an interim analysis of the Korean Stroke Cohort for Functioning and Rehabilitation. Among 10,636 patients with first-ever stroke, a total of 3215 patients with normal cognitive function three months post-stroke were included in the analysis. PSD was defined using the Korean Geriatric Depression Scale Short Form (K-GDS-SF) at three months. Cognitive aging was defined as a decline in the Korean version of the Mini-Mental Status Examination (K-MMSE) score to less than the second percentile. Results: The hazard ratio (HR) of PSD for cognitive decline was 2.16 (95% CI, 1.34−3.50, p < 0.01) in the older group (age ≥65 years), and 1.02 (95% CI, 0.50−2.07, n.s.) in the younger group (age <65 years). When the older group was divided by sex, the HR was 2.50 (95% CI, 1.26−4.96, p < 0.01) in male patients and 1.80 (95% CI, 0.93−3.51, n.s.) in female patients. However, women showed a higher incidence of cognitive decline in both the PSD and no PSD groups. Among K-GDS-SF factors, “Negative judgment about the past, present, and future” increased the HR of PSD in older male patients. Conclusions: Early PSD increased the HR for cognitive decline in older stroke patients, mainly in males. Specifically, older male patients with negative thinking were at increased risk of cognitive decline. The findings also suggest that older women may be at risk for cognitive decline. Therefore, preventive interventions for cognitive decline should be tailored differently for men and women.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.