ArticleJournal of personalized medicine2022
Enhanced Recovery after Surgery (ERAS) in DIEP-Flap Breast Reconstructions-A Comparison of Two Reconstructive Centers with and without ERAS-Protocol.
Article in Journal of personalized medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Effectiveness and safety of liposomal bupivacaine in autologous breast reconstruction: a systematic review.Frontiers in medicine · 2026Pooled it
- Optimising the unilateral DIEP flap breast reconstruction: A United Kingdom-Netherlands multi-centre comparative study.JPRAS open · 2026Article
- Implementation Science in Breast Reconstruction: A Guide to Closing the Research-to-practice Gap.Plastic and reconstructive surgery. Global open · 2025Article
- Improving the Patient Experience in Breast Reconstruction: ERAS and Beyond.Journal of clinical medicine · 2025Review
- ERASing Confounders: Measuring Differences in Post Operative Pathways.Plastic surgery (Oakville, Ont.) · 2025Article
- Moving Toward the Outpatient DIEP Flap: Factors Influencing Early Discharge.Plastic and reconstructive surgery · 2025Article
- Intrathecal Morphine vs Paravertebral Nerve Blocks for Analgesia After Breast Reconstruction With Abdominally Based Free Flaps.Aesthetic surgery journal · 2025Article
- Present and Future of Autologous Breast Reconstruction: Advancing Techniques to Minimize Morbidity and Complications, Enhancing Quality of Life and Patient Satisfaction.Journal of clinical medicine · 2025Article
- Using Social Media to Understand Patient Perceptions of Deep Inferior Epigastric Perforator Flap Reconstruction.Plastic and reconstructive surgery. Global open · 2025Article
- Article
- Outcomes and Current State of Deep Inferior Epigastric Perforator Flap Surgery in Peru and Mexico.Plastic and reconstructive surgery. Global open · 2025Article
- Web-based machine learning application for interpretable prediction of prolonged length of stay after lumbar spinal stenosis surgery: a retrospective cohort study with explainable AI.Frontiers in physiology · 2025Article
- Sustainability in Reconstructive Breast Surgery: An Eco-audit of the Deep Inferior Epigastric Perforator Flap Pathway.Plastic and reconstructive surgery. Global open · 2024Article
- Liposomal Bupivacaine Analgesia in Deep Inferior Epigastric Perforator Flap Breast Reconstruction: A Retrospective Cohort Study.Plastic and reconstructive surgery. Global open · 2024Article
- Moving the needle: a narrative review of enhanced recovery protocols in breast reconstruction.Annals of translational medicine · 2023Review
- A Single-center Comparison of Unipedicled and Bipedicled Diep Flap Early Outcomes in 98 Patients.Plastic and reconstructive surgery. Global open · 2023Article
- The Scarless Neo-Umbilicus in DIEP-Flap Breast Reconstruction.Journal of personalized medicine · 2023Article
- Comparing complications and perioperative teams in microsurgical breast reconstruction: retrospective cohort study.Gland surgery · 2022Article
- Autologous Breast Reconstruction with Free Nipple-Areola Graft after Circumareolar (Skin Reducing) Mastectomy.Journal of personalized medicine · 2022Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Enhanced recovery after surgery (ERAS) is established for autologous breast reconstruction. ERAS leads to a shortened hospital stay and improved outcome after elective surgery. In this retrospective, two-center case−control study, we compared two different treatment regimens for patients undergoing a DIEP-flap breast reconstruction from two centers, one with an established ERAS protocol and one without. All patients with DIEP breast reconstructions over the period of 12 months were included. The primary outcome measure was the length of hospital stay (LOS) in days. A total of 79 patients with 95 DIEP-flaps were analyzed. In group A (ERAS) 42 patients were operated with DIEP flaps, in group B (non-ERAS) 37 patients. LOS was significantly reduced in the ERAS group (4.51 days) compared to the non-ERAS group (6.32; p < 0.001). Multivariate analysis showed that, in group A, LOS is significantly affected by surgery duration. BMI in the ERAS group had no effect on LOS. In group B a higher BMI resulted in a significantly higher LOS. In multivariate analysis, neither age nor type for surgery (primary/secondary/after neoadjuvant therapy, etc.) affected LOS. In both groups, no systemic or flap-related complications were observed. Comparing two reconstructive centers with and without implemented ERAS, ERAS led to a significantly decreased LOS for all patients. ERAS implementation does not result in an increased complication rate or flap loss. Postoperative pain can be well managed with basic analgesia using NSAID when intraoperative blocks are applied. The reduced use of opioids was well tolerated. With implementation of ERAS the recovery experience can be enhanced making autologous breast reconstructions more available and attractive for various patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.