ReviewLife (Basel, Switzerland)2022
Comparison of In Vivo Intradiscal Pressure between Sitting and Standing in Human Lumbar Spine: A Systematic Review and Meta-Analysis.
Review in Life (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 26 citations in OpenAlex.
- The reliability and validity of the 30-second chair sit-to-stand test and the five-repetition sit-to-stand test in individuals following lumbar spinal surgery.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- From Bench to Bedside: Translational Barriers in Mesenchymal Stem Cell Therapy for Intervertebral Disc Degeneration.Bioengineering (Basel, Switzerland) · 2026Review
- Intradiscal pressure distributions in degenerated intervertebral discs: A biomechanical investigation.Journal of medical and biological engineering · 2025Article
- The impact of Tai Chi's "Xuling Dingjin" posture on lumbar biomechanics during stair descent.Frontiers in sports and active living · 2025Article
- Correlation between clinical and MRI findings in disc herniation in the lumbosacral region.Irish journal of medical science · 2024Article
- PLGA/BK microspheres targeting the bradykinin signaling pathway as a therapeutic strategy to delay intervertebral disc degeneration.Communications biology · 2024Article
- Epidural pressure measurement using a fiber-optic sensor (proof-of-principle in vivo animal trial).Animal models and experimental medicine · 2024Article
- Chronic Low Back Pain: History, Symptoms, Pain Mechanisms, and Treatment.Life (Basel, Switzerland) · 2024Review
- Finite Element Analysis of Stress Distribution and Range of Motion in Discogenic Back Pain.Neurospine · 2024Article
- Rotation-traction manipulation induced intradiskal pressure changes in cervical spine-anFrontiers in bioengineering and biotechnology · 2024Article
- Differences in walking and running parameters in elementary school students with and without backpacks.Work (Reading, Mass.) · 2024Article
- Biomechanical Effects of Different Sitting Postures and Physiologic Movements on the Lumbar Spine: A Finite Element Study.Bioengineering (Basel, Switzerland) · 2023Article
- The Relationship between Sleeping Position and Sleep Quality: A Flexible Sensor-Based Study.Sensors (Basel, Switzerland) · 2022Article
- Neglected problem: Influence of school bag on lumbar segment in children.Frontiers in pediatrics · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundNon-specific low back pain (LBP) is highly prevalent today. Disc degeneration could be one of the causes of non-specific LBP, and increased intradiscal pressure (IDP) can potentially induce disc degeneration. The differences in vivo IDP in sitting and standing postures have been studied, but inconsistent results have been reported. The primary objective of this systematic review is to compare the differences in vivo IDP between sitting and standing postures. The secondary objective of this review is to compare effect size estimates between (1) dated and more recent studies and (2) healthy and degenerated intervertebral discs.
methodsAn exhaustive search of six electronic databases for studies published before November 2021 was conducted. Articles measuring in vivo IDP in sitting and standing postures were included. Two independent researchers conducted the screening and data extraction.
resultsTen studies that met the inclusion criteria were included in the systematic review, and seven studies with nine independent groups were included in meta-analyses. The sitting posture induces a significantly higher IDP on the lumbar spine (SMD: 0.87; 95% CI = [0.33, 1.41]) than the standing posture. In studies published after 1990 and subjects with degenerated discs, there are no differences in vivo IDP between both postures.
conclusionsSitting causes higher loads on the lumbar spine than standing in the normal discs, but recent studies do not support this conclusion. Furthermore, the degenerated discs showed no difference in IDP in both postures.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.