Evidence map›Paper›PMID 35330197›Full record

ReviewLife (Basel, Switzerland)2022

Near-Infrared Fluorescence Tumor-Targeted Imaging in Lung Cancer: A Systematic Review.

Lisanne K A Neijenhuis, Lysanne D A N de Myunck, Okker D Bijlstra, Peter J K Kuppen, Denise E Hilling, Frank J Borm, Danielle Cohen, J Sven D Mieog, Willem H Steup, Jerry Braun and 3 more

Open access · goldAbstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

  1. Intraoperative molecular imaging of colorectal lung metastases with SGM-101: a feasibility study.European journal of nuclear medicine and molecular imaging · 2024
    Trial
  2. Article
  3. Review
  4. Review
  5. Article
  6. Preoperative localization of pulmonary nodules: virtual bronchoscopic navigation vs a 4‑hook localization needle.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2025
    Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. State of the Art in Lung Nodule Localization.Journal of clinical medicine · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Lisanne K A NeijenhuisDepartment of Surgery, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.ORCID 0000-0003-2972-9172
Lysanne D A N de MyunckDepartment of Surgery, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.ORCID 0000-0002-4035-6605
Okker D BijlstraDepartment of Surgery, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
Peter J K KuppenDepartment of Surgery, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.ORCID 0000-0002-0294-3251
Denise E HillingDepartment of Surgery, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.ORCID 0000-0002-5875-6164
Frank J BormDepartment of Pulmonology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
Danielle CohenDepartment of Pathology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
J Sven D MieogDepartment of Surgery, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
Willem H SteupDepartment of Surgery, HAGA Hospital, 2545 AA The Hague, The Netherlands.ORCID 0000-0002-1948-5672
Jerry BraunDepartment of Cardiothoracic Surgery, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
Jacobus BurggraafCentre for Human Drug Research, 2333 CL Leiden, The Netherlands.
Alexander L VahrmeijerDepartment of Surgery, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
Merlijn HuttemanDepartment of Surgery, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.ORCID 0000-0001-8528-2913
Leiden University Medical Center · NLCentre for Human Drug Research · NLHaga Hospital · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung cancer is the most common cancer type worldwide, with non-small cell lung cancer (NSCLC) being the most common subtype. Non-disseminated NSCLC is mainly treated with surgical resection. The intraoperative detection of lung cancer can be challenging, since small and deeply located pulmonary nodules can be invisible under white light. Due to the increasing use of minimally invasive surgical techniques, tactile information is often reduced. Therefore, several intraoperative imaging techniques have been tested to localize pulmonary nodules, of which near-infrared (NIR) fluorescence is an emerging modality. In this systematic review, the available literature on fluorescence imaging of lung cancers is presented, which shows that NIR fluorescence-guided lung surgery has the potential to identify the tumor during surgery, detect additional lesions and prevent tumor-positive resection margins.

Indexed as

fluorescence-guided surgerylung cancermolecular imagingnear-infrared fluorescence imagingoptical imaging

Identifiers

PMID35330197
PMCPMC8950608
OpenAlexW4220871189

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.