Evidence map›Paper›PMID 35330169›Full record

ReviewLife (Basel, Switzerland)2022

As We Drink and Breathe: Adverse Health Effects of Microcystins and Other Harmful Algal Bloom Toxins in the Liver, Gut, Lungs and Beyond.

Apurva Lad, Joshua D Breidenbach, Robin C Su, Jordan Murray, Rebecca Kuang, Alison Mascarenhas, John Najjar, Shivani Patel, Prajwal Hegde, Mirella Youssef and 7 more

Open access · goldAbstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 1 pooled it
11.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 1 synthesis or guideline pooled it, 114 citations in OpenAlex.

  1. Guideline
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Ecotoxicology ofToxins · 2026
    Review
  14. Environmental risk factors for liver cancer.Hepatology (Baltimore, Md.) · 2025
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Life Course Exposure to Cyanobacteria and Amyotrophic Lateral Sclerosis Survival.International journal of environmental research and public health · 2025
    Article
  20. HABS-BLOCKS© InhibitedMicroorganisms · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 1 country.

Apurva LadCollege of Medicine and Life Science, University of Toledo, Toledo, OH 43614, USA.ORCID 0000-0001-6073-7432
Joshua D BreidenbachCollege of Medicine and Life Science, University of Toledo, Toledo, OH 43614, USA.ORCID 0000-0002-5892-1879
Robin C SuCollege of Medicine and Life Science, University of Toledo, Toledo, OH 43614, USA.
Jordan MurrayCollege of Medicine and Life Science, University of Toledo, Toledo, OH 43614, USA.
Rebecca KuangCollege of Medicine and Life Science, University of Toledo, Toledo, OH 43614, USA.
Alison MascarenhasCollege of Medicine and Life Science, University of Toledo, Toledo, OH 43614, USA.
John NajjarCollege of Medicine and Life Science, University of Toledo, Toledo, OH 43614, USA.
Shivani PatelCollege of Medicine and Life Science, University of Toledo, Toledo, OH 43614, USA.
Prajwal HegdeCollege of Medicine and Life Science, University of Toledo, Toledo, OH 43614, USA.
Mirella YoussefCollege of Medicine and Life Science, University of Toledo, Toledo, OH 43614, USA.
Jason BreulerCollege of Medicine and Life Science, University of Toledo, Toledo, OH 43614, USA.
Andrew L KleinhenzCollege of Medicine and Life Science, University of Toledo, Toledo, OH 43614, USA.ORCID 0000-0002-7088-0088
Andrew P AultDepartment of Chemistry, University of Michigan, Ann Arbor, MI 48109, USA.ORCID 0000-0002-7313-8559
Judy A WestrickLumigen Instrumentation Center, Department of Chemistry, Wayne State University, Detroit, MI 48202, USA.
Nikolai N ModyanovCollege of Medicine and Life Science, University of Toledo, Toledo, OH 43614, USA.
David J KennedyCollege of Medicine and Life Science, University of Toledo, Toledo, OH 43614, USA.ORCID 0000-0001-5265-0142
Steven T HallerCollege of Medicine and Life Science, University of Toledo, Toledo, OH 43614, USA.ORCID 0000-0002-6919-6342
University of Toledo · USUniversity of Michigan · USWayne State University · US

Funding

Inhalation Exposure to Aerosolized Cyanotoxins Worsens Pre-Existing Asthma via Activation of Granulocytic InflammationF31HL160178 · NHLBI · UNIVERSITY OF TOLEDO HEALTH SCI CAMPUS · PI BREIDENBACH, JOSHUA DAVID · 2021 to 2022
$60k
NHLBI NIH HHS F31 HL160178
6 · The paper itself

Abstract

Freshwater harmful algal blooms (HABs) are increasing in number and severity worldwide. These HABs are chiefly composed of one or more species of cyanobacteria, also known as blue-green algae, such as

Indexed as

cyanotoxinsharmful algal bloomsmicrocystin-LRpre-existing disease

Identifiers

PMID35330169
PMCPMC8950847
OpenAlexW4220746595

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.