Evidence map›Paper›PMID 35330157›Full record

ArticleLife (Basel, Switzerland)2022

2-Fluorofucose Attenuates Hydrogen Peroxide-Induced Oxidative Stress in HepG2 Cells via Nrf2/keap1 and NF-κB Signaling Pathways.

Mengjue Tu, Xingshuo Fan, Jianan Shi, Shengnan Jing, Xiaole Xu, Yuqin Wang

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Mengjue TuDepartment of Pharmacology, School of Pharmacy, Nantong University, Nantong 226001, China.
Xingshuo FanDepartment of Pharmacology, School of Pharmacy, Nantong University, Nantong 226001, China.
Jianan ShiDepartment of Pharmacology, School of Pharmacy, Nantong University, Nantong 226001, China.
Shengnan JingDepartment of Pharmacology, School of Pharmacy, Nantong University, Nantong 226001, China.
Xiaole XuDepartment of Pharmacology, School of Pharmacy, Nantong University, Nantong 226001, China.
Yuqin WangDepartment of Pharmacology, School of Pharmacy, Nantong University, Nantong 226001, China.
Nantong University · CNJiangsu Provincial Center for Disease Control and Prevention · CN

Funding

National Natural Science Foundation of China 31500649Natural Science Foundation of Nantong City JC2019101
6 · The paper itself

Abstract

Fucosylation is one of the most important glycan terminal modifications that affects multiple biological activities of proteins. 2-Fluorofucose (2FF), its specific inhibitor, has recently been reported to reveal numerous biological effects by blocking fucosylation both in vitro and in vivo. The current study aimed to evaluate the effect of 2FF on hydrogen peroxide (H

Indexed as

2-fluorofucosefucosylationNF-κBNrf2oxidative stress

Identifiers

PMID35330157
PMCPMC8950221
OpenAlexW4221045182

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.