Evidence map›Paper›PMID 35330062›Full record

ArticleJournal of clinical medicine2022

Mathematical Modeling to Predict COVID-19 Infection and Vaccination Trends.

Bogdan Doroftei, Ovidiu-Dumitru Ilie, Nicoleta Anton, Sergiu-Ioan Timofte, Ciprian Ilea

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Bogdan DorofteiFaculty of Medicine, University of Medicine and Pharmacy "Grigore T. Popa", University Street, No. 16, 700115 Iasi, Romania.ORCID 0000-0002-6618-141X
Ovidiu-Dumitru IlieDepartment of Biology, Faculty of Biology, "Alexandru Ioan Cuza" University, Carol I Avenue, No. 20A, 700505 Iasi, Romania.ORCID 0000-0002-4023-1765
Nicoleta AntonFaculty of Medicine, University of Medicine and Pharmacy "Grigore T. Popa", University Street, No. 16, 700115 Iasi, Romania.ORCID 0000-0002-4987-5049
Sergiu-Ioan TimofteDepartment of Biology, Faculty of Biology, "Alexandru Ioan Cuza" University, Carol I Avenue, No. 20A, 700505 Iasi, Romania.ORCID 0000-0001-6155-2296
Ciprian IleaFaculty of Medicine, University of Medicine and Pharmacy "Grigore T. Popa", University Street, No. 16, 700115 Iasi, Romania.
Grigore T. Popa University of Medicine and Pharmacy · ROAlexandru Ioan Cuza University · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: COVID-19 caused by the Severe Acute Respiratory Syndrome Coronavirus 2 placed the health systems around the entire world in a battle against the clock. While most of the existing studies aimed at forecasting the infections trends, our study focuses on vaccination trend(s). Material and methods: Based on these considerations, we used standard analyses and ARIMA modeling to predict possible scenarios in Romania, the second-lowest country regarding vaccinations from the entire European Union. Results: With approximately 16 million doses of vaccine against COVID-19 administered, 7,791,250 individuals had completed the vaccination scheme. From the total, 5,058,908 choose Pfizer−BioNTech, 399,327 Moderna, 419,037 AstraZeneca, and 1,913,978 Johnson & Johnson. With a cumulative 2147 local and 17,542 general adverse reactions, the most numerous were reported in recipients of Pfizer−BioNTech (1581 vs. 8451), followed by AstraZeneca (138 vs. 6033), Moderna (332 vs. 1936), and Johnson & Johnson (96 vs. 1122). On three distinct occasions have been reported >50,000 individuals who received the first or second dose of a vaccine and >30,000 of a booster dose in a single day. Due to high reactogenicity in case of AZD1222, and time of launching between the Pfizer−BioNTech and Moderna vaccine could be explained differences in terms doses administered. Furthermore, ARIMA(1,1,0), ARIMA(1,1,1), ARIMA(0,2,0), ARIMA(2,1,0), ARIMA(1,2,2), ARI-MA(2,2,2), ARIMA(0,2,2), ARIMA(2,2,2), ARIMA(1,1,2), ARIMA(2,2,2), ARIMA(2,1,1), ARIMA(2,2,1), and ARIMA (2,0,2) for all twelve months and in total fitted the best models. These were regarded according to the lowest MAPE, p-value (p < 0.05, p < 0.01, and p < 0.001) and through the Ljung−Box test (p < 0.05, p < 0.01, and p < 0.001) for autocorrelations. Conclusions: Statistical modeling and mathematical analyses are suitable not only for forecasting the infection trends but the course of a vaccination rate as well.

Indexed as

ARIMACOVID-19dosesreactogenicityRomaniaSARS-CoV-2vaccination scheme

Identifiers

PMID35330062
PMCPMC8956009
OpenAlexW4220661849

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.