Evidence map›Paper›PMID 35329966›Full record

ArticleJournal of clinical medicine2022

Feasibility of Outpatient Stem Cell Transplantation in Multiple Myeloma and Risk Factors Predictive of Hospital Admission.

Kristin Larsen, Horace Spencer, Meera Mohan, Clyde Bailey, Kerri Hill, Mathew Kottarathara, Richa Parikh, Shadiqul Hoque, Amani Erra, Angel A Mitma and 15 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 2 institutions in 1 country.

Kristin LarsenMyeloma Center, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Horace SpencerDepartment of Biostatistics, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.ORCID 0000-0001-8176-881X
Meera MohanMedical College of Wisconsin Cancer Center, Froedtert Hospital, Milwaukee, WI 53226, USA.
Clyde BaileyMyeloma Center, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Kerri HillMyeloma Center, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Mathew KottaratharaMyeloma Center, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Richa ParikhMyeloma Center, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Shadiqul HoqueMyeloma Center, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Amani ErraMyeloma Center, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Angel A MitmaMyeloma Center, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Pankaj MathurMyeloma Center, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Lakshmi YarlagaddaMyeloma Center, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Sravani GundarlapalliMyeloma Center, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Yetunde OgunsesanMyeloma Center, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Munawwar HussainMyeloma Center, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Nishanth ThalambeduMyeloma Center, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Jaskirat SehtiMyeloma Center, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Samer Al HadidiMyeloma Center, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.ORCID 0000-0003-4297-8042
Sharmilan ThanendrarajanMyeloma Center, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Monica GraziuttiMyeloma Center, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Maurizio ZangariMyeloma Center, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Bart BarlogieMyeloma Center, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Frits van RheeMyeloma Center, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Guido TricotMyeloma Center, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Carolina SchinkeMyeloma Center, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.ORCID 0000-0002-2699-1741
University of Arkansas for Medical Sciences · USFroedtert Hospital · US

Funding

Expanding Translational Research in ArkansasUL1TR003107 · NCATS · UNIV OF ARKANSAS FOR MED SCIS · PI JAMES, LAURA P · 2019 to 2023
$21.6M
NCATS NIH HHS UL1 TR003107
6 · The paper itself

Abstract

High-dose chemotherapy followed by autologous stem cell transplantation (ASCT) remains the standard of care for multiple myeloma (MM) patients. Although outpatient ASCT has been shown to be safe and feasible, the procedure is overall rare with most patients in the US undergoing inpatient ASCT. Furthermore, hospitalization rates for patients that undergo outpatient ASCT remain high. Adequate markers that predict hospitalization during outpatient ASCT are lacking, yet would be of great clinical value to select patients that are suited to outpatient ASCT. In this study we aimed to elucidate differences between planned outpatient and inpatient ASCT and further evaluated clinical characteristics that are significantly associated with hospitalization during planned outpatient hospitalization. Factors that were significantly associated with a planned inpatient ASCT included an advanced MM disease stage, worse performance status as well as non-Caucasian race, while low albumin levels and female gender were significantly associated with hospitalization during outpatient ASCT. The results of this analysis provide crucial knowledge of factors that are associated with planned inpatient ASCT and hospitalization during outpatient ASCT and could guide the treating physician in decision-making and further facilitate outpatient transplantation.

Indexed as

autologous stem cell transplantationhospitalizationmultiple myeloma

Identifiers

PMID35329966
PMCPMC8955129
OpenAlexW4220724867

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.