ArticleJournal of clinical medicine2022
Association of Subclinical Hypothyroidism with Present and Absent Anti-Thyroid Antibodies with PCOS Phenotypes and Metabolic Profile.
Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The impact of subclinical hypothyroidism on core reproductive hormones and ovarian endocrine status in patients with polycystic ovary syndrome: a systematic review and meta-analysis.Frontiers in endocrinology · 2026Pooled it
- Thyroid Autoimmunity in Polycystic Ovary Syndrome: Phenotype Distribution, HDL-Cholesterol, and Data-Driven Clusters in a Retrospective Cohort Study.Medicina (Kaunas, Lithuania) · 2026Article
- Thyroid autoimmunity does not delineate a cardiometabolic or androgenic phenotype in women with polycystic ovary syndrome: a pre-specified cross-sectional analysis.Frontiers in endocrinology · 2026Article
- Chronic inflammatory activity in women with normogonadotropic anovulation complicated by subclinical thyroid dysfunction: a prospective cohort study.Frontiers in endocrinology · 2026Article
- Prevalence of anti-thyroid peroxidase antibodies among women with polycystic ovary syndrome.Scientific reports · 2025Article
- Ovarian function measures in normogonadotropic anovulation and subclinical thyroid dysfunction: a prospective cohort study.Endocrine · 2025Article
- Autoimmune Processes and Chronic Inflammation as Independent Risk Factors for Metabolic Complications in Women with Polycystic Ovary Syndrome.Metabolites · 2025Article
- Article
- Thyroid autoimmunity in different phenotypes of polycystic ovary syndrome: a single-center experience.Journal of endocrinological investigation · 2024Article
- Is thyroid function associated with polycystic ovary syndrome? A bidirectional Mendelian randomization study.Endocrine · 2024Article
- Endometriosis, polycystic ovary syndrome, and the thyroid: a review.Endocrine connections · 2024Review
- The role of the thyroid in polycystic ovary syndrome.Frontiers in endocrinology · 2023Review
- Polycystic ovary syndrome and thyroid disorder: a comprehensive narrative review of the literature.Frontiers in endocrinology · 2023Review
- Exome sequencing to explore the possibility of predicting genetic susceptibility to the joint occurrence of polycystic ovary syndrome and Hashimoto's thyroiditis.Frontiers in immunology · 2023Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPolycystic ovary syndrome (PCOS) and subclinical hypothyroidism (SCH) often coexist, but implications of the co-occurrence of two disorders have not yet been established. The objective is to conclude whether SCH with present or absent anti-thyroid antibodies (ATA) impacts on the PCOS phenotype and alters biochemical or clinical parameters.
methodsA retrospective cohort study was conducted in a tertiary reference center. Clinical and biochemical parameters of women with PCOS were analyzed.
resultsA total of 367 women with PCOS were included in the study, 114 (31.1%) of whom were diagnosed with SCH and 16 (4.4%) with autoimmune thyroiditis (AIT). Among all parameters studied, the strongest relationship with SCH was confirmed for insulin resistance and dyslipidemia. SCH was an independent risk factor for insulin resistance. In SCH the additional presence of ATA did not exacerbate the metabolic disorders. There was no significant association of any PCOS phenotype with SCH, nor with the presence of circulating ATA. There was no significant difference in hormonal parameters and mFerriman-Gallwey scale score between women with PCOS with and without SCH.
conclusionsSCH alters metabolic, but not hormonal, parameters in PCOS. The diagnosis of SCH does not exclude the diagnosis of PCOS. The potential effect of positive ATA was insignificant.
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