Evidence map›Paper›PMID 35329408›Full record

ArticleInternational journal of environmental research and public health2022

Developmental Disorder Probability Scores at 6-18 Years Old in Relation to In-Utero/Peripartum Antiretroviral Drug Exposure among Ugandan Children.

Jorem Emmillian Awadu, Alla Sikorskii, Sarah Zalwango, Audrey Coventry, Bruno Giordani, Amara E Ezeamama

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Jorem Emmillian AwaduDepartment of Psychiatry, Michigan State University, East Lansing, MI 48824, USA.ORCID 0000-0002-5151-738X
Alla SikorskiiDepartment of Psychiatry, Michigan State University, East Lansing, MI 48824, USA.
Sarah ZalwangoDirectorate of Public Health and Environment, Kampala Capital City Authority, Kampala 00256, Uganda.
Audrey CoventrySpectrum Health Incorporated, Lansing, MI 49085, USA.
Bruno GiordaniDepartment of Psychiatry, University of Michigan, Ann Arbor, MI 48109, USA.
Amara E EzeamamaDepartment of Psychiatry, Michigan State University, East Lansing, MI 48824, USA.ORCID 0000-0003-2164-8802
Michigan State University · USKampala Capital City Authority · UGSpectrum Health · USUniversity of Michigan · US

Funding

Perinatal HIV infection/exposure, stress and long-term functional survival in Ugandan adolescentsR21HD088169 · NICHD · MICHIGAN STATE UNIVERSITY · PI EZEAMAMA, AMARA E · 2017 to 2018
$696k
CIPHER Grant program of the International AIDS Society 327-EZENIH HHS National Institutes of health (3R21HD088169-02S1, and R21HD088169)
6 · The paper itself

Abstract

(1) We examined the hypothesis that in utero/peripartum antiretroviral (IPA) exposure may affect the likelihood of developmental disorders-i.e., attention deficit and hyperactivity disorder (ADHD), autism spectrum disorder (ASD), and functional impairment (FI). (2) Children and their primary caregivers were enrolled and followed for 12 months. The sample included 250 children perinatally HIV-infected (CPHIV), 250 children HIV-exposed and uninfected (CHEU) of women living with HIV, and 250 children HIV unexposed and uninfected (CHUU) at 6-18 years of age. CHEU's IPA exposure -type was established via medical records and categorized as no IPA, single-dose nevirapine with/without zidovudine (SdNVP ± AZT), SdNVP + AZT + Lamivudine (3TC), or combination ART (cART). Developmental disorders were assessed at months 0, 6, and 12 per caregiver response to standardized questions from the third edition of

Indexed as

Anti-HIV AgentsAutism Spectrum DisorderHIV InfectionsPregnancy Complications, InfectiousAdolescentAnti-Retroviral AgentsChildDevelopmental DisabilitiesFemaleHumansLamivudinePeripartum PeriodPregnancyProbabilityUgandaZidovudineAnti-HIV AgentsAnti-Retroviral AgentsLamivudineZidovudineADHDadolescentsASDchildrenfunctional impairmentHIV-exposed uninfectedperinatal HIV infectionperipartum ART exposureresiliencyUganda

Identifiers

PMID35329408
PMCPMC8955488
OpenAlexW4220905005

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.