Evidence map›Paper›PMID 35329213›Full record

ArticleInternational journal of environmental research and public health2022

Concentration of Selected Metalloproteinases and Osteocalcin in the Serum and Synovial Fluid of Obese Women with Advanced Knee Osteoarthritis.

Jaromir Jarecki, Teresa Małecka-Masalska, Ewa Kosior-Jarecka, Wojciech Widuchowski, Piotr Krasowski, Martina Gutbier, Maciej Dobrzyński, Tomasz Blicharski

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 32 citations in OpenAlex.

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  7. Journal of clinical medicine · 2025
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  13. The Oral Administration ofCurrent issues in molecular biology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Jaromir JareckiDepartment of Rehabilitation and Orthopaedics, Medical University of Lublin, 20-059 Lublin, Poland.ORCID 0000-0002-6866-3850
Teresa Małecka-MasalskaPhysiology Department, Medical University of Lublin, 20-059 Lublin, Poland.ORCID 0000-0003-3384-0324
Ewa Kosior-JareckaDepartment Diagnostics and Microsurgery of Glaucoma, Medical University of Lublin, 20-079 Lublin, Poland.ORCID 0000-0002-5251-7998
Wojciech WiduchowskiDepartament of Physiotherapy, The College of Physiotherapy, 50-038 Wrocław, Poland.ORCID 0000-0002-3684-7823
Piotr KrasowskiDepartment of Orthopaedics and Traumatology, Regional Hospital in Chełm, 22-100 Chełm, Poland.ORCID 0000-0001-9979-0011
Martina GutbierDepartment of Pediatric Dentistry and Preclinical Dentistry, Wrocław Medical University, Krakowska 26, 50-425 Wrocław, Poland.
Maciej DobrzyńskiDepartment of Pediatric Dentistry and Preclinical Dentistry, Wrocław Medical University, Krakowska 26, 50-425 Wrocław, Poland.ORCID 0000-0003-2368-1534
Tomasz BlicharskiDepartment of Rehabilitation and Orthopaedics, Medical University of Lublin, 20-059 Lublin, Poland.ORCID 0000-0001-9747-8817
Medical University of Lublin · PLWroclaw Medical University · PLAcademy of Physiotherapy in Wrocław · PLState School of Higher Education in Chełm · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the study was to evaluate the levels of selected MMPs (matrix metalloproteinases) and osteocalcin in the serum and synovial fluid of obese women with osteoarthritis and their correlations with clinical status. The studied group consisted of 39 overweight females undergoing primary total knee arthroplasty due to osteoarthritis (OA). The staging of knee OA was evaluated according to the Ahlbӓck and Kellgren-Lawrence scores. Synovial fluid and peripheral blood samples were obtained. The levels of selected MMPs and osteocalcin were assessed using commercial ELISA kits. The mean value of MMP3 was significantly higher in patients with more advanced disease in both serum (

Indexed as

Matrix Metalloproteinase 9Osteoarthritis, KneeBiomarkersFemaleHumansMatrix Metalloproteinase 13Matrix Metalloproteinase 3ObesityOsteocalcinSynovial FluidBiomarkersMatrix Metalloproteinase 13Matrix Metalloproteinase 3Matrix Metalloproteinase 9MMP13 protein, humanMMP3 protein, humanMMP9 protein, humanOsteocalcinfemalekneematrix metalloproteinasesobesityosteoarthritisosteocalcin

Identifiers

PMID35329213
PMCPMC8953048
OpenAlexW4220668876

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.