ArticleInternational journal of environmental research and public health2022
Cognitive Function among World Trade Center-Exposed Community Members with Mental Health Symptoms.
Article in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.
- Assessing neurocognitive outcomes in PTSD: a multilevel meta-analytical approach.European journal of psychotraumatology · 2025Pooled it
- Mechanistic signatures of comorbid PTSD with cognitive impairment implicate cortisol-induced neural toxicity.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- Increased Aβ40 in plasma is associated with severity of exposure to airborne pollutants at the World Trade Center: a cross-sectional study of neurological biomarkers.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025Article
- World Trade Center response activities and cognitive health: A moderated mediation study of the role of surgical/nuisance dust mask usage.Neurotoxicology · 2025Article
- Association between World Trade Center disaster exposures and body mass index in community members enrolled at World Trade Center Environmental Health Center.Environmental pollution (Barking, Essex : 1987) · 2025Article
- Cross-sectional association between posttraumatic stress and cognition is moderated by pulmonary functioning in world trade center responders.American journal of industrial medicine · 2024Article
- Incidence of Dementia Before Age 65 Years Among World Trade Center Attack Responders.JAMA network open · 2024Article
- Post-traumatic stress disorder symptom remission and cognition in a large cohort of civilian women.Psychological medicine · 2024Article
- Posttraumatic Stress Disorder Mediates the Association between Traumatic World Trade Center Dust Cloud Exposure and Ongoing Systemic Inflammation in Community Members.International journal of environmental research and public health · 2022Article
- Molecular Clustering Analysis of Blood Biomarkers in World Trade Center Exposed Community Members with Persistent Lower Respiratory Symptoms.International journal of environmental research and public health · 2022Article
- Heart failure and late-onset Alzheimer's disease: A Mendelian randomization study.Frontiers in genetics · 2022Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
The World Trade Center Environmental Health Center (WTC EHC), is a federally designated clinical center of excellence for surveillance and treatment of WTC disaster exposed community members (WTC Survivors). Cognitive impairment (CI) has been extensively described in WTC responders and a concern for progressive impairment in all WTC disaster exposed groups has been raised. Cognitive status, however, has not been systematically characterized in the WTC Survivor population. We describe cognitive status in a subgroup of the Survivor population referred for mental health evaluation (N = 480) in the WTC EHC as measured by scores on the Montreal Cognitive Assessment (MoCA) instrument, and examine their association with WTC exposures and individual-level covariates including PTSD and depression screening inventory scores. In regression analyses, probable cognitive impairment (MoCA score < 26) was found in 59% of the study subjects and was significantly associated with age, race/ethnicity, education, income, depression and PTSD scores. Being caught in the dust cloud on 11 September 2011 was significantly associated with cognitive impairment even after controlling for the above. These data suggest an association with cognitive dysfunction in WTC Survivors with exposure to the toxic dust/fumes and psychological stress from the 9/11 terrorist attack and warrant further systematic study.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.