Evidence map›Paper›PMID 35329028›Full record

ArticleInternational journal of environmental research and public health2022

Differential Bioaccumulation Patterns of α, β-Hexachlorobenzene and Dicofol in Adipose Tissue from the GraMo Cohort (Southern Spain).

Inmaculada Salcedo-Bellido, Esperanza Amaya, Celia Pérez-Díaz, Anabel Soler, Fernando Vela-Soria, Pilar Requena, Rocío Barrios-Rodríguez, Ruth Echeverría, Francisco M Pérez-Carrascosa, Raquel Quesada-Jiménez and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Inmaculada Salcedo-BellidoDepartamento de Medicina Preventiva y Salud Pública, Universidad de Granada, 18071 Granada, Spain.ORCID 0000-0003-4601-198X
Esperanza AmayaInstituto de Investigación Biosanitaria (ibs. GRANADA), 18014 Granada, Spain.
Celia Pérez-DíazDepartamento de Medicina Preventiva y Salud Pública, Universidad de Granada, 18071 Granada, Spain.ORCID 0000-0002-6550-1629
Anabel SolerDepartamento de Medicina Preventiva y Salud Pública, Universidad de Granada, 18071 Granada, Spain.
Fernando Vela-SoriaInstituto de Investigación Biosanitaria (ibs. GRANADA), 18014 Granada, Spain.
Pilar RequenaDepartamento de Medicina Preventiva y Salud Pública, Universidad de Granada, 18071 Granada, Spain.
Rocío Barrios-RodríguezDepartamento de Medicina Preventiva y Salud Pública, Universidad de Granada, 18071 Granada, Spain.ORCID 0000-0002-8772-636X
Ruth EcheverríaDepartamento de Medicina Preventiva y Salud Pública, Universidad de Granada, 18071 Granada, Spain.ORCID 0000-0001-5886-6753
Francisco M Pérez-CarrascosaDepartamento de Medicina Preventiva y Salud Pública, Universidad de Granada, 18071 Granada, Spain.ORCID 0000-0003-4809-095X
Raquel Quesada-JiménezInstituto de Investigación Biosanitaria (ibs. GRANADA), 18014 Granada, Spain.
Piedad Martín-OlmedoInstituto de Investigación Biosanitaria (ibs. GRANADA), 18014 Granada, Spain.ORCID 0000-0002-3343-9760
Juan Pedro ArrebolaDepartamento de Medicina Preventiva y Salud Pública, Universidad de Granada, 18071 Granada, Spain.
Universidad de Granada · ESInstituto de Investigación Biosanitaria de Granada · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To identify bioaccumulation patterns of α-, β- hexachlorocyclohexane (HCH) and dicofol in relation to sociodemographic, dietary, and lifestyle factors, adipose tissue samples of 387 subjects from GraMo cohort in Southern Spain were analyzed. Potential predictors of these organochlorine pesticides (OCP) levels were collected by face-to-face interviews and assessed by multivariable linear and logistic regression. OCPs were detected in 84.2% (β-HCH), 21.7% (α-HCH), and 19.6% (dicofol) of the population. β-HCH levels were positively related to age, body mass index (BMI), mother's occupation in agriculture during pregnancy, living in Poniente and Alpujarras, white fish, milk and water consumption, and negatively related to being male, living near to an agricultural area, working ≥10 years in agriculture, and beer consumption. Detectable α-HCH levels were positively related to age, BMI, milk consumption, mother's occupation in agriculture during pregnancy, and negatively with residence in Poniente and Alpujarras, Granada city, and Granada Metropolitan Area. Residence near to an agricultural area, smoking habit, white fish and water consumption, and living in Poniente and Alpujarras, Granada city and Granada Metropolitan Area were negatively associated with detectable dicofol levels. Our study revealed different bioaccumulation patterns of α, β-HCH and dicofol, probably due to their dissimilar period of use, and emphasize the need for assessing the exposure to frequently overlooked pollutants.

Indexed as

Hydrocarbons, ChlorinatedPesticidesAdipose TissueAnimalsBioaccumulationDicofolFemaleHexachlorocyclohexaneHumansMalePregnancySpainbeta-hexachlorocyclohexaneDicofolHexachlorocyclohexaneHydrocarbons, ChlorinatedPesticidesdicofolexposure assessmenthuman adipose tissuepredictorsα-hexachlorocyclohexaneβ-hexachlorocyclohexane

Identifiers

PMID35329028
PMCPMC8954870
OpenAlexW4220722950

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.