Evidence map›Paper›PMID 35328999›Full record

ArticleInternational journal of environmental research and public health2022

Building the Momentum for A Stronger Pharmaceutical System in Africa.

Silvia Ussai, Caterina Chillotti, Erminia Stochino, Arianna Deidda, Giovanni Ambu, Lorenzo Anania, Alberto Boccalini, Flavia Colombo, Alessandra Ferrari, Daniele Pala and 3 more

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Health expenditure in Africa: examining the synergistic impact of economic policy uncertainty and governance quality.The European journal of health economics : HEPAC : health economics in prevention and care · 2026
    Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Silvia UssaiClinical Pharmacology and Toxicology, University of Cagliari, 09124 Cagliari, Italy.
Caterina ChillottiDepartment of Biomedical Sciences, Section of Neuroscience and Clinical Pharmacology, University of Cagliari, 09124 Cagliari, Italy.
Erminia StochinoDepartment of Biomedical Sciences, Section of Neuroscience and Clinical Pharmacology, University of Cagliari, 09124 Cagliari, Italy.
Arianna DeiddaDepartment of Biomedical Sciences, Section of Neuroscience and Clinical Pharmacology, University of Cagliari, 09124 Cagliari, Italy.
Giovanni AmbuClinical Pharmacology and Toxicology, University of Cagliari, 09124 Cagliari, Italy.
Lorenzo AnaniaClinical Pharmacology and Toxicology, University of Cagliari, 09124 Cagliari, Italy.
Alberto BoccaliniClinical Pharmacology and Toxicology, University of Cagliari, 09124 Cagliari, Italy.
Flavia ColomboClinical Pharmacology and Toxicology, University of Cagliari, 09124 Cagliari, Italy.
Alessandra FerrariClinical Pharmacology and Toxicology, University of Cagliari, 09124 Cagliari, Italy.
Daniele PalaClinical Pharmacology and Toxicology, University of Cagliari, 09124 Cagliari, Italy.
Enrica PudduClinical Pharmacology and Toxicology, University of Cagliari, 09124 Cagliari, Italy.
Giulia RapalloClinical Pharmacology and Toxicology, University of Cagliari, 09124 Cagliari, Italy.
Marco PistisDepartment of Biomedical Sciences, Section of Neuroscience and Clinical Pharmacology, University of Cagliari, 09124 Cagliari, Italy.ORCID 0000-0002-4622-3205

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite impressive progress, nearly two billion people worldwide have no access to essential medicines. The COVID-19 pandemic revealed Africa's vulnerability due to its reliance on imports for most vaccines, medicines, and other health product needs. The vaccine manufacturing is complex and requires massive financial investments, with global, regional, and national regulatory structures introducing consistent and urgent reforms to assure the quality and safety of medicines. In 2020, there were approximately 600 pharmaceutical manufacturers in Africa, 80% of which were concentrated in eight countries: Egypt, Algeria, Morocco, Tunisia, Nigeria, Ghana, Kenya, and South Africa. Only 4 countries had more than 50 manufacturers, while 22 countries had no local production. Out of the 600, around 25% were multinational companies. Africa is equally affected by modest scaled capacities substantially engaging in packaging and labelling, and occasionally fill and finish steps, facing criticalities in terms of solvent domestic markets. This article discusses the challenges in the development of a local pharmaceutical manufacturing in Africa and reflects on the importance of the momentum for strengthening the local medical production capacity in the continent as a critical opportunity for advancing universal health coverage (UHC).

Indexed as

COVID-19Drugs, EssentialHumansNigeriaPandemicsUniversal Health InsuranceDrugs, EssentialAfricaCOVID-19pharmaceutical system strengthening

Identifiers

PMID35328999
PMCPMC8956013

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.