Evidence map›Paper›PMID 35328882›Full record

ArticleInternational journal of environmental research and public health2022

Patrizia Danesi, Matteo Petini, Christian Falcaro, Michela Bertola, Elisa Mazzotta, Tommaso Furlanello, Mark Krockenberger, Richard Malik

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. A NovelJournal of fungi (Basel, Switzerland) · 2024
    Article
  5. Meta-Analysis and Systematic Literature Review of the GenusJournal of fungi (Basel, Switzerland) · 2023
    Article
  6. Article
  7. Detection ofJournal of fungi (Basel, Switzerland) · 2023
    Article
  8. Oculosystemic pneumocystosis in 2 sibling Chihuahuas.Journal of veterinary internal medicine
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Patrizia DanesiParasitology, Mycology and Medical Enthomology, Istituto Zooprofilattico Sperimentale delle Venezie, Legnaro, 35020 Padua, Italy.ORCID 0000-0002-6738-2125
Matteo PetiniClinica e Laboratorio Veterinario San Marco, Veggiano, 35030 Padua, Italy.
Christian FalcaroParasitology, Mycology and Medical Enthomology, Istituto Zooprofilattico Sperimentale delle Venezie, Legnaro, 35020 Padua, Italy.ORCID 0000-0001-5105-8454
Michela BertolaParasitology, Mycology and Medical Enthomology, Istituto Zooprofilattico Sperimentale delle Venezie, Legnaro, 35020 Padua, Italy.ORCID 0000-0001-6600-7369
Elisa MazzottaParasitology, Mycology and Medical Enthomology, Istituto Zooprofilattico Sperimentale delle Venezie, Legnaro, 35020 Padua, Italy.ORCID 0000-0003-2369-8467
Tommaso FurlanelloClinica e Laboratorio Veterinario San Marco, Veggiano, 35030 Padua, Italy.ORCID 0000-0003-1935-5146
Mark KrockenbergerVeterinary Pathology Diagnostic Services, Sydney School of Veterinary Science, The University of Sydney, Sydney, NSW 2006, Australia.ORCID 0000-0002-8168-4795
Richard MalikCentre for Veterinary Education, The University of Sydney, Sydney, NSW 2006, Australia.ORCID 0000-0002-6025-194X
Istituto Zooprofilattico Sperimentale delle Venezie · ITThe University of Sydney · AUVeterinary Oncological Center · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pneumocystis is an atypical fungus that resides in the pulmonary parenchyma of many mammals, including humans and dogs. Immunocompetent human hosts are usually asymptomatically colonised or show subtle clinical signs, but some immunocompromised people can develop florid life-threatening Pneumocystis pneumonia (PCP). Since much less is known concerning Pneumocystis in dogs, we posit the question: can Pneumocystis colonization be present in dogs with inflammatory airway or lung disease caused by other pathogens or disease processes? In this study, Pneumocystis DNA was detected in bronchoalveolar lavage fluid (BALF) of 22/255 dogs (9%) with respiratory distress and/or chronic cough. Although young dogs (<1 year-of-age) and pedigree breeds were more often Pneumocystis-qPCR positive than older dogs and crossbreds, adult dogs with other infectious conditions and/or a history of therapy-resistant pulmonary disease could also be qPCR-positive, including two patients with suppression of the immune system. Absence of pathognomonic clinical or radiographic signs render it impossible to convincingly discriminate between overt PCP versus other lung/airway disease processes colonised by P. canis. It is possible that colonisation with P. canis might play a certain role as a co-pathogen in some canine patients with lower respiratory disease.

Indexed as

PneumocystisPneumonia, PneumocystisAnimalsBronchoalveolar Lavage FluidDogsHumansLungMammalsPlant BreedingbronchitiscanineCavalier King Charles spanieldogPneumocystis canispneumocystosispneumonia

Identifiers

PMID35328882
PMCPMC8955813
OpenAlexW4220915011

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.