Evidence map›Paper›PMID 35328832›Full record

ArticleInternational journal of molecular sciences2022

Nucleobase-Derived Nitrones: Synthesis and Antioxidant and Neuroprotective Activities in an In Vitro Model of Ischemia-Reperfusion.

Beatriz Chamorro, Iwona E Głowacka, Joanna Gotkowska, Rafał Gulej, Dimitra Hadjipavlou-Litina, Francisco López-Muñoz, José Marco-Contelles, Dorota G Piotrowska, María Jesús Oset-Gasque

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Phosphorylated Nitrones-Synthesis and Applications.Molecules (Basel, Switzerland) · 2025
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Beatriz ChamorroDepartment of Biochemistry and Molecular Biology, Faculty of Pharmacy, Complutense University of Madrid, Plaza Ramón y Cajal s/n, Ciudad Universitaria, 28040 Madrid, Spain.
Iwona E GłowackaBioorganic Chemistry Laboratory, Faculty of Pharmacy, Medical University of Lodz, Muszyńskiego 1, 90-151 Lodz, Poland.ORCID 0000-0001-7567-5860
Joanna GotkowskaBioorganic Chemistry Laboratory, Faculty of Pharmacy, Medical University of Lodz, Muszyńskiego 1, 90-151 Lodz, Poland.
Rafał GulejBioorganic Chemistry Laboratory, Faculty of Pharmacy, Medical University of Lodz, Muszyńskiego 1, 90-151 Lodz, Poland.ORCID 0000-0002-9958-707X
Dimitra Hadjipavlou-LitinaDepartment of Pharmaceutical Chemistry, School of Pharmacy, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.ORCID 0000-0002-1844-350X
Francisco López-MuñozFaculty of Health, Camilo José Cela University, Castillo de Alarcón 49, Villanueva de la Cañada, 28692 Madrid, Spain.ORCID 0000-0002-5188-6038
José Marco-ContellesLaboratory of Medicinal Chemistry, Institute of Organic Chemistry (CSIC), Juan de la Cierva 3, 28006 Madrid, Spain.
Dorota G PiotrowskaBioorganic Chemistry Laboratory, Faculty of Pharmacy, Medical University of Lodz, Muszyńskiego 1, 90-151 Lodz, Poland.ORCID 0000-0003-3792-8796
María Jesús Oset-GasqueDepartment of Biochemistry and Molecular Biology, Faculty of Pharmacy, Complutense University of Madrid, Plaza Ramón y Cajal s/n, Ciudad Universitaria, 28040 Madrid, Spain.ORCID 0000-0002-7223-0222
Medical University of Lodz · PLUniversidad Complutense de Madrid · ESAristotle University of Thessaloniki · GRInstituto de Química Orgánica General · ESResearch Institute Hospital 12 de Octubre · ES

Funding

Medical University of Lodz 503/3-014-01/503-31-001MINECO (Spain) SAF2015-65586-RNational Science Centre of Lodz (Poland) UMO-2013/11/N/NZ7/00723Universidad Camilo José Cela (Madrid) Spain UCJC 2015-12 and UCJC 2020-03
6 · The paper itself

Abstract

Herein, we report the synthesis, antioxidant, and neuroprotective properties of some nucleobase-derived nitrones named

Indexed as

NeuroblastomaNeuroprotective AgentsAntioxidantsHumansIschemiaNitrogen OxidesReperfusionSuperoxidesUracilAntioxidantsNeuroprotective AgentsNitrogen OxidesnitronesSuperoxidesUracilantioxidantsapoptosisbrain ischemianecrosisneuroprotectionnucleobase-derived nitronesoxidative stress

Identifiers

PMID35328832
PMCPMC8955307
OpenAlexW4220882686

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.