Evidence map›Paper›PMID 35328829›Full record

ArticleInternational journal of molecular sciences2022

Therapeutic Treatment of Superoxide Dismutase 1 (G93A) Amyotrophic Lateral Sclerosis Model Mice with Medical Ozone Decelerates Trigeminal Motor Neuron Degeneration, Attenuates Microglial Proliferation, and Preserves Monocyte Levels in Mesenteric Lymph Nodes.

Michael Bette, Eileen Cors, Carolin Kresse, Burkhard Schütz

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Michael BetteInstitute of Anatomy and Cell Biology, Philipps-University, 35037 Marburg, Germany.ORCID 0000-0002-7336-8207
Eileen CorsInstitute of Anatomy and Cell Biology, Philipps-University, 35037 Marburg, Germany.
Carolin KresseInstitute of Anatomy and Cell Biology, Philipps-University, 35037 Marburg, Germany.
Burkhard SchützInstitute of Anatomy and Cell Biology, Philipps-University, 35037 Marburg, Germany.ORCID 0000-0003-4473-1959
Philipps University of Marburg · DE

Funding

Deutsche Gesellschaft für Muskelkranke Sc10/6
6 · The paper itself

Abstract

Amyotrophic lateral sclerosis (ALS) is an incurable and lethal neurodegenerative disease in which progressive motor neuron loss and associated inflammation represent major pathology hallmarks. Both the prevention of neuronal loss and neuro-destructive inflammation are still unmet challenges. Medical ozone, an ozonized oxygen mixture (O

Indexed as

Amyotrophic Lateral SclerosisNeurodegenerative DiseasesOzoneAnimalsCell ProliferationDisease Models, AnimalDisease ProgressionInflammationLymph NodesMiceMice, Inbred C57BLMice, TransgenicMicrogliaMonocytesNerve DegenerationSuperoxide DismutaseOzoneSuperoxide DismutaseSuperoxide Dismutase-1adaptive immune systemamyotrophicmonocyteneurodegenerationneuroinflammationozone

Identifiers

PMID35328829
PMCPMC8950555
OpenAlexW4220855851

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.