ReviewInternational journal of molecular sciences2022
Mechanisms and Applications of Bacterial Sporulation and Germination in the Intestine.
Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 48 citations in OpenAlex.
- Ecological Engineering of the Human Gut Microbiome: A Narrative Review and Framework for Next-Generation Therapeutics.Microorganisms · 2026Review
- Convergent Gut Microbiome Remodeling Across Ischemic Stroke, Myocardial Infarction, and Longevity Reveals a Shared Ecological Signature of Aging and Disease.International journal of molecular sciences · 2026Article
- A Spore-Forming Bacillus Strain FM2 Isolated from Fish Market Runoffs with Remarkable Probiotic Attributes for Aquaculture Settings.Probiotics and antimicrobial proteins · 2026Article
- Biofilm Formation and Spore-Mediated Persistence of Clostridium perfringens in Meat and Poultry Processing Environments and Their Implications for Control Strategies.Journal of food science · 2026Review
- Revisiting Strategies for Bacterial Enumeration: The Case for Viable but Nonculturable (VBNC) Cells in Supplement Products.Probiotics and antimicrobial proteins · 2026Review
- Review
- Dietary calcium citrate enhances nutrient digestibility and modulates cecal microbiota function in pre-laying hens.Veterinary world · 2026Article
- Surface Display of Duck Hepatitis A Virus Type 1 VP1 Protein on Bacillus subtilis Spores Elicits Specific Systemic and Mucosal Immune Responses on Mice.Probiotics and antimicrobial proteins · 2025Article
- Genomic and functional characterization of ureolytic Bacillus bombysepticus QCSJ3 and its application in self-healing cementitious composites through encapsulation.World journal of microbiology & biotechnology · 2025Article
- Phenotypic Characterization of Pectinase-Producing Alkaliphilic Microbial Isolates From Lake Bogoria, Baringo County, Kenya.MicrobiologyOpen · 2025Article
- Rewiring the Brain Through the Gut: Insights into Microbiota-Nervous System Interactions.Current issues in molecular biology · 2025Review
- Metabolic pathways associated with Firmicutes prevalence in the gut of multiple livestock animals and humans.Animal microbiome · 2025Article
- Winning the battle of intestinal peace withFrontiers in microbiology · 2025Review
- Phenotypic and Genomic Insights Into Bacillus spp. and Peribacillus spp. of Spanish Olive Groves With Biotechnological Potential.Environmental microbiology reports · 2024Article
- Uncovering newMicrobiology spectrum · 2024Article
- Microbes as medicine.Annals of the New York Academy of Sciences · 2024Review
- Pangenomes of human gut microbiota uncover links between genetic diversity and stress response.Cell host & microbe · 2024Article
- Microbial Therapeutics in Oncology: A Comprehensive Review of Bacterial Role in Cancer Treatment.Cureus · 2024Review
- Molecular mechanisms of precise timing in cell lysis.Biophysical journal · 2024Article
- Genetic and Phenotypic Characterization ofMicroorganisms · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recent studies have suggested a major role for endospore forming bacteria within the gut microbiota, not only as pathogens but also as commensal and beneficial members contributing to gut homeostasis. In this review the sporulation processes, spore properties, and germination processes will be explained within the scope of the human gut. Within the gut, spore-forming bacteria are known to interact with the host's immune system, both in vegetative cell and spore form. Together with the resistant nature of the spore, these characteristics offer potential for spores' use as delivery vehicles for therapeutics. In the last part of the review, the therapeutic potential of spores as probiotics, vaccine vehicles, and drug delivery systems will be discussed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.