Evidence map›Paper›PMID 35328786›Full record

ArticleInternational journal of molecular sciences2022

Pro-Calcific Environment Impairs Ischaemia-Driven Angiogenesis.

Jocelyne Mulangala, Emma J Akers, Emma L Solly, Panashe M Bamhare, Laura A Wilsdon, Nathan K P Wong, Joanne T M Tan, Christina A Bursill, Stephen J Nicholls, Belinda A Di Bartolo

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Jocelyne MulangalaDiscipline of Medicine, University of Adelaide, Adelaide, SA 5005, Australia.
Emma J AkersDiscipline of Medicine, University of Adelaide, Adelaide, SA 5005, Australia.
Emma L SollyDiscipline of Medicine, University of Adelaide, Adelaide, SA 5005, Australia.ORCID 0000-0001-9992-1181
Panashe M BamhareVascular Research Centre, Heart Health Theme, South Australian Health and Medical Research Institute, Adelaide, SA 5000, Australia.
Laura A WilsdonVascular Research Centre, Heart Health Theme, South Australian Health and Medical Research Institute, Adelaide, SA 5000, Australia.
Nathan K P WongVascular Research Centre, Heart Health Theme, South Australian Health and Medical Research Institute, Adelaide, SA 5000, Australia.
Joanne T M TanDiscipline of Medicine, University of Adelaide, Adelaide, SA 5005, Australia.ORCID 0000-0003-1875-4882
Christina A BursillDiscipline of Medicine, University of Adelaide, Adelaide, SA 5005, Australia.ORCID 0000-0002-0682-8760
Stephen J NichollsMonash Cardiovascular Research Centre, Victorian Heart Institute, Monash University, Melbourne, VIC 3168, Australia.
Belinda A Di BartoloFaculty of Medicine and Health, School of Medicine, The University of Sydney, Sydney, NSW 2006, Australia.
South Australian Health and Medical Research Institute · AUThe University of Sydney · AUMonash University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peripheral arterial disease (PAD) is characterised by accelerated arterial calcification and impairment in angiogenesis. Studies implicate vascular calcification as a contributor to PAD, but the mechanisms remain unclear. We aimed to determine the effect of calcification on ischaemia-driven angiogenesis. Human coronary artery endothelial cells (ECs) were treated with calcification medium (CM: CaCl

Indexed as

Peripheral Arterial DiseaseVascular CalcificationAnimalsCarbon DioxideEndothelial CellsHumansHypoxiaIschemiaMiceNeovascularization, PathologicCarbon Dioxideangiogenesisischaemiaperipheral arterial diseasevascular calcification

Identifiers

PMID35328786
PMCPMC8954938
OpenAlexW4220666404

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.