Evidence map›Paper›PMID 35328711›Full record

ArticleInternational journal of molecular sciences2022

SARS-CoV-2 Spike Protein and Mouse Coronavirus Inhibit Biofilm Formation by

Mun Fai Loke, Indresh Yadav, Teck Kwang Lim, Johan R C van der Maarel, Lok-To Sham, Vincent T Chow

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Calcium RescuesMicroorganisms · 2024
    Article
  3. Review
  4. Genomics: Infectious Disease and Host-Pathogen Interaction.International journal of molecular sciences · 2023
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Mun Fai LokeInfectious Diseases Translational Research Program, Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117545, Singapore.
Indresh YadavDepartment of Physics, Faculty of Science, National University of Singapore, Singapore 117542, Singapore.
Teck Kwang LimProtein and Proteomics Centre, Department of Biological Sciences, Faculty of Science, National University of Singapore, Singapore 117558, Singapore.
Johan R C van der MaarelDepartment of Physics, Faculty of Science, National University of Singapore, Singapore 117542, Singapore.ORCID 0000-0001-5560-0298
Lok-To ShamInfectious Diseases Translational Research Program, Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117545, Singapore.
Vincent T ChowInfectious Diseases Translational Research Program, Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117545, Singapore.ORCID 0000-0003-2634-6213
National University of Singapore · SG

Funding

National University of Singapore N571000016001
6 · The paper itself

Abstract

The presence of co-infections or superinfections with bacterial pathogens in COVID-19 patients is associated with poor outcomes, including increased morbidity and mortality. We hypothesized that SARS-CoV-2 and its components interact with the biofilms generated by commensal bacteria, which may contribute to co-infections. This study employed crystal violet staining and particle-tracking microrheology to characterize the formation of biofilms by

Indexed as

AntibiosisBiofilmsAnimalsCoinfectionCoronavirusGene Expression Regulation, BacterialHumansMiceMicrobial InteractionsSARS-CoV-2SerogroupSpike Glycoprotein, CoronavirusStaphylococcus aureusStreptococcus pneumoniaeSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2biofilmcoronavirusCOVID-19MHVnucleocapsidS1 and S2 subunitsSARS-CoV-2spike proteinStaphylococcus aureusStreptococcus pneumoniae

Identifiers

PMID35328711
PMCPMC8950232
OpenAlexW4220978141

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.