Evidence map›Paper›PMID 35328634›Full record

ArticleInternational journal of molecular sciences2022

4-Arylthiosemicarbazide Derivatives as Toxoplasmic Aromatic Amino Acid Hydroxylase Inhibitors and Anti-inflammatory Agents.

Adrian Bekier, Anna Brzostek, Agata Paneth, Bożena Dziadek, Jarosław Dziadek, Justyna Gatkowska, Katarzyna Dzitko

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
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  5. Inhibition ofJournal of enzyme inhibition and medicinal chemistry · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Adrian BekierDepartment of Molecular Microbiology, Faculty of Biology and Environmental Protection, University of Lodz, 90-237 Lodz, Poland.ORCID 0000-0002-4980-1074
Anna BrzostekLaboratory of Genetics and Physiology of Mycobacterium, Institute of Medical Biology, Polish Academy of Sciences, 93-232 Lodz, Poland.ORCID 0000-0002-7335-9853
Agata PanethDepartment of Organic Chemistry, Faculty of Pharmacy, Medical University of Lublin, 20-093 Lublin, Poland.
Bożena DziadekDepartment of Molecular Microbiology, Faculty of Biology and Environmental Protection, University of Lodz, 90-237 Lodz, Poland.ORCID 0000-0002-4942-7385
Jarosław DziadekLaboratory of Genetics and Physiology of Mycobacterium, Institute of Medical Biology, Polish Academy of Sciences, 93-232 Lodz, Poland.ORCID 0000-0003-1427-884X
Justyna GatkowskaDepartment of Molecular Microbiology, Faculty of Biology and Environmental Protection, University of Lodz, 90-237 Lodz, Poland.ORCID 0000-0002-0559-1706
Katarzyna DzitkoDepartment of Molecular Microbiology, Faculty of Biology and Environmental Protection, University of Lodz, 90-237 Lodz, Poland.ORCID 0000-0002-3265-0409
University of Łódź · PLPolish Academy of Sciences · PLMedical University of Lublin · PL

Funding

National Science Center 2018/31/N/NZ6/03004
6 · The paper itself

Abstract

Approximately one-third of the human population is infected with the intracellular cosmopolitan protozoan

Indexed as

Anti-Inflammatory AgentsAntiprotozoal AgentsMixed Function OxygenasesSemicarbazidesToxoplasmaEscherichia coliHumansNF-kappa BTyrosineAnti-Inflammatory AgentsAntiprotozoal AgentsMixed Function OxygenasesNF-kappa BSemicarbazidesTyrosinebradyzoiteNF-κB pathway inhibitionthiosemicarbazideToxoplasma gondiityrosine

Identifiers

PMID35328634
PMCPMC8955734
OpenAlexW4220820412

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.