Evidence map›Paper›PMID 35328605›Full record

ArticleInternational journal of molecular sciences2022

BRET-Based Biosensors to Measure Agonist Efficacies in Histamine H

Eléonore W E Verweij, Reggie Bosma, Meichun Gao, Jelle van den Bor, Betty Al Araaj, Sabrina M de Munnik, Xiaoyuan Ma, Rob Leurs, Henry F Vischer

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Receptor-Ligand Binding: Effect of Mechanical Factors.International journal of molecular sciences · 2023
    Review
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  5. Article
  6. Review
  7. Article
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  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Eléonore W E VerweijDivision of Medicinal Chemistry, Faculty of Science, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit Amsterdam, 1081 HZ Amsterdam, The Netherlands.
Reggie BosmaDivision of Medicinal Chemistry, Faculty of Science, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit Amsterdam, 1081 HZ Amsterdam, The Netherlands.
Meichun GaoDivision of Medicinal Chemistry, Faculty of Science, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit Amsterdam, 1081 HZ Amsterdam, The Netherlands.
Jelle van den BorDivision of Medicinal Chemistry, Faculty of Science, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit Amsterdam, 1081 HZ Amsterdam, The Netherlands.ORCID 0000-0002-2411-2379
Betty Al AraajDivision of Medicinal Chemistry, Faculty of Science, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit Amsterdam, 1081 HZ Amsterdam, The Netherlands.
Sabrina M de MunnikDivision of Medicinal Chemistry, Faculty of Science, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit Amsterdam, 1081 HZ Amsterdam, The Netherlands.
Xiaoyuan MaDivision of Medicinal Chemistry, Faculty of Science, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit Amsterdam, 1081 HZ Amsterdam, The Netherlands.ORCID 0000-0002-5768-017X
Rob LeursDivision of Medicinal Chemistry, Faculty of Science, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit Amsterdam, 1081 HZ Amsterdam, The Netherlands.ORCID 0000-0003-1354-2848
Henry F VischerDivision of Medicinal Chemistry, Faculty of Science, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit Amsterdam, 1081 HZ Amsterdam, The Netherlands.ORCID 0000-0002-0184-6337
Vrije Universiteit Amsterdam · NL

Funding

China Scholarship Council 201703250074China Scholarship Council 202006310027Dutch Research Council 711.013.014Innovative Medicines Initiative 115366
6 · The paper itself

Abstract

The histamine H

Indexed as

Biosensing TechniquesHistaminebeta-ArrestinsEnergy TransferG-Protein-Coupled Receptor KinasesGTP-Binding ProteinsHEK293 CellsHumansReceptors, G-Protein-CoupledReceptors, Histamine H1beta-ArrestinsG-Protein-Coupled Receptor KinasesGTP-Binding ProteinsHistamineReceptors, G-Protein-CoupledReceptors, Histamine H1biased signalingBRET assayGPCRGPCR kinaseG proteinH1Rhistamineβ-arrestin

Identifiers

PMID35328605
PMCPMC8953162
OpenAlexW4220957560

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.