ArticleInternational journal of molecular sciences2022
Controlled Hydrolysis of Odorants Schiff Bases in Low-Molecular-Weight Gels.
Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 18 citations in OpenAlex.
- High-performance caffeic acid-based superhydrophilic membranes for efficient removal of microplastics-oil co-contaminants.Nature communications · 2026Article
- Transparent Organogels as a Medium for the Light-Induced Conversion from Spiropyran to Merocyanine.Gels (Basel, Switzerland) · 2023Article
- A pH/enzyme dual responsive PMB spatiotemporal release hydrogel promoting chronic wound repair.Journal of nanobiotechnology · 2023Article
- Advances in Gelatin Bioinks to Optimize Bioprinted Cell Functions.Advanced healthcare materials · 2023Review
- Controlled Lactonization ofGels (Basel, Switzerland) · 2023Article
- Biomolecule-Based Biomaterials and Their Application in Drug Delivery Systems.International journal of molecular sciences · 2023Article
- Delivery of Active Peptides by Self-Healing, Biocompatible and Supramolecular Hydrogels.Molecules (Basel, Switzerland) · 2023Article
- Recent Advances in the Preparation of Delivery Systems for the Controlled Release of Scents.International journal of molecular sciences · 2023Review
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Imines or Schiff bases (SB) are formed by the condensation of an aldehyde or a ketone with a primary amine, with the removal of a water molecule. Schiff bases are central molecules in several biological processes for their ability to form and cleave by small variation of the medium. We report here the controlled hydrolysis of four SBs that may be applied in the fragrance industry, as they are profragrances all containing odorant molecules: methyl anthranilate as primary amine, and four aldehydes (cyclamal, helional, hydroxycitronellal and triplal) that are very volatile odorants. The SB stability was assessed over time by HPLC-MS in neutral or acidic conditions, both in solution and when trapped in low molecular weight gels. Our results demonstrate that it is possible to control the hydrolysis of the Schiff bases in the gel environment, thus tuning the quantity of aldehyde released and the persistency of the fragrance.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.