Evidence map›Paper›PMID 35328492›Full record

ReviewInternational journal of molecular sciences2022

The Fight against Cancer by Microgravity: The Multicellular Spheroid as a Metastasis Model.

Daniela Grimm, Herbert Schulz, Marcus Krüger, José Luis Cortés-Sánchez, Marcel Egli, Armin Kraus, Jayashree Sahana, Thomas J Corydon, Ruth Hemmersbach, Petra M Wise and 2 more

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 67 citations in OpenAlex.

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  20. Targeted Cancer Therapy-on-A-Chip.Advanced healthcare materials · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 4 countries.

Daniela GrimmDepartment of Microgravity and Translational Regenerative Medicine, Medical Faculty, University Hospital Magdeburg, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.ORCID 0000-0002-4991-3105
Herbert SchulzDepartment of Microgravity and Translational Regenerative Medicine, Medical Faculty, University Hospital Magdeburg, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.
Marcus KrügerDepartment of Microgravity and Translational Regenerative Medicine, Medical Faculty, University Hospital Magdeburg, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.ORCID 0000-0003-1120-0246
José Luis Cortés-SánchezDepartment of Microgravity and Translational Regenerative Medicine, Medical Faculty, University Hospital Magdeburg, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.ORCID 0000-0002-4646-9520
Marcel EgliSpace Biology Group, Institute of Medical Engineering, Lucerne University of Applied Sciences and Arts, 6002 Hergiswil, Switzerland.
Armin KrausDepartment of Microgravity and Translational Regenerative Medicine, Medical Faculty, University Hospital Magdeburg, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.ORCID 0000-0001-6557-2163
Jayashree SahanaDepartment of Biomedicine, The Faculty of Health, Aarhus University, Ole Worms Allé 4, 8000 Aarhus, Denmark.
Thomas J CorydonDepartment of Biomedicine, The Faculty of Health, Aarhus University, Ole Worms Allé 4, 8000 Aarhus, Denmark.ORCID 0000-0003-3588-6350
Ruth HemmersbachGravitational Biology, Institute of Aerospace Medicine, German Aerospace Center, Linder Höhe, 51147 Cologne, Germany.ORCID 0000-0001-5308-6715
Petra M WiseThe Saban Research Institute, Children's Hospital Los Angeles, University of Southern California, 4650 Sunset Blvd., Los Angeles, CA 90027, USA.
Manfred InfangerDepartment of Microgravity and Translational Regenerative Medicine, Medical Faculty, University Hospital Magdeburg, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.
Markus WehlandDepartment of Microgravity and Translational Regenerative Medicine, Medical Faculty, University Hospital Magdeburg, Otto von Guericke University, Universitätsplatz 2, 39106 Magdeburg, Germany.ORCID 0000-0002-8160-859X
University Hospital Magdeburg · DEAarhus University · DKDeutsches Zentrum für Luft- und Raumfahrt e. V. (DLR) · DELucerne University of Applied Sciences and Arts · CHUniversity of Southern California · US

Funding

German Aerospace Center 500WB1924German Aerospace Center 50WB1524
6 · The paper itself

Abstract

Cancer is a disease exhibiting uncontrollable cell growth and spreading to other parts of the organism. It is a heavy, worldwide burden for mankind with high morbidity and mortality. Therefore, groundbreaking research and innovations are necessary. Research in space under microgravity (µ

Indexed as

NeoplasmsWeightlessnessHumansMaleOrganoidsSpheroids, CellularWeightlessness Simulationbreast cancercancer stem cellsclinostatcolorectal cancerliver cancermicrogravitymulticellular spheroidsomics studiesorganoidsprostate cancerrandom positioning machinerotating wall vesselspaceflightthyroid cancer

Identifiers

PMID35328492
PMCPMC8953941
OpenAlexW4220884990

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.