Evidence map›Paper›PMID 35328455›Full record

ArticleInternational journal of molecular sciences2022

On the Efficacy of ZnO Nanostructures against SARS-CoV-2.

Maria Chiara Sportelli, Margherita Izzi, Daniela Loconsole, Anna Sallustio, Rosaria Anna Picca, Roberto Felici, Maria Chironna, Nicola Cioffi

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
6.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 47 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Antiviral Activity of Zinc Oxide Nanoparticles against SARS-CoV-2.International journal of molecular sciences · 2023
    Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Maria Chiara SportelliChemistry Department, University of Bari Aldo Moro, Via Orabona, 4, 70126 Bari, Italy.ORCID 0000-0002-8832-2770
Margherita IzziChemistry Department, University of Bari Aldo Moro, Via Orabona, 4, 70126 Bari, Italy.ORCID 0000-0001-5158-2352
Daniela LoconsoleDepartment of Biomedical Sciences and Human Oncology-Hygiene Section, University of Bari Aldo Moro, Piazza Giulio Cesare, 11, 70124 Bari, Italy.ORCID 0000-0003-2057-9745
Anna SallustioAzienda Ospedaliero-Universitaria Consorziale Policlinico di Bari, Piazza G. Cesare, 11, 70124 Bari, Italy.
Rosaria Anna PiccaChemistry Department, University of Bari Aldo Moro, Via Orabona, 4, 70126 Bari, Italy.ORCID 0000-0001-8033-098X
Roberto FeliciCNR-SPIN, Area Della Ricerca di Tor Vergata, Via del Fosso del Cavaliere, 100, 00133 Rome, Italy.
Maria ChironnaDepartment of Biomedical Sciences and Human Oncology-Hygiene Section, University of Bari Aldo Moro, Piazza Giulio Cesare, 11, 70124 Bari, Italy.ORCID 0000-0002-1043-1256
Nicola CioffiChemistry Department, University of Bari Aldo Moro, Via Orabona, 4, 70126 Bari, Italy.ORCID 0000-0002-6765-440X
University of Bari Aldo Moro · ITAzienda Universitaria Ospedaliera Consorziale - Policlinico Bari · IT

Funding

Ministry of Education, Universities and Research H99J21017320006Regione Puglia 435A866B
6 · The paper itself

Abstract

In 2019, the new coronavirus disease (COVID-19), related to the severe acute respiratory syndrome coronavirus (SARS-CoV-2), started spreading around the word, giving rise to the world pandemic we are still facing. Since then, many strategies for the prevention and control of COVID-19 have been studied and implemented. In addition to pharmacological treatments and vaccines, it is mandatory to ensure the cleaning and disinfection of the skin and inanimate surfaces, especially in those contexts where the contagion could spread quickly, such as hospitals and clinical laboratories, schools, transport, and public places in general. Here, we report the efficacy of ZnO nanoparticles (ZnONPs) against SARS-CoV-2. NPs were produced using an ecofriendly method and fully characterized; their antiviral activity was tested in vitro against SARS-CoV-2, showing a decrease in viral load between 70% and 90%, as a function of the material's composition. Application of these nano-antimicrobials as coatings for commonly touched surfaces is envisaged.

Indexed as

Antiviral AgentsColorimetryCOVID-19HumansMicrobial Sensitivity TestsMicroscopy, Electron, TransmissionNanostructuresPandemicsPhotoelectron SpectroscopySARS-CoV-2Spectroscopy, Fourier Transform InfraredTreatment OutcomeViral LoadX-Ray DiffractionZinc OxideAntiviral AgentsZinc OxideantiviralCOVID-19green synthesisnano-antimicrobialsnasopharyngeal swabnucleocapsid proteinSARS-CoV-2zinc oxide

Identifiers

PMID35328455
PMCPMC8950216
OpenAlexW4220993458

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.