Evidence map›Paper›PMID 35328414›Full record

ArticleInternational journal of molecular sciences2022

Compartmentalized Innate Immune Response of Human Fetal Membranes against

Andrea Olmos-Ortiz, Mayra Hernández-Pérez, Pilar Flores-Espinosa, Gabriela Sedano, Addy Cecilia Helguera-Repetto, Óscar Villavicencio-Carrisoza, María Yolotzin Valdespino-Vazquez, Arturo Flores-Pliego, Claudine Irles, Bruno Rivas-Santiago and 3 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Research Progress on perinatalFrontiers in microbiology · 2026
    Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. High Glucose Promotes Inflammation and Weakens Placental Defenses againstInternational journal of molecular sciences · 2023
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Andrea Olmos-OrtizDepartamento de Inmunobioquímica, Instituto Nacional de Perinatología (INPer), Mexico City 11000, Mexico.ORCID 0000-0002-5456-9695
Mayra Hernández-PérezDepartamento de Inmunobioquímica, Instituto Nacional de Perinatología (INPer), Mexico City 11000, Mexico.
Pilar Flores-EspinosaDepartamento de Inmunobioquímica, Instituto Nacional de Perinatología (INPer), Mexico City 11000, Mexico.ORCID 0000-0003-2140-3629
Gabriela SedanoDepartamento de Inmunobioquímica, Instituto Nacional de Perinatología (INPer), Mexico City 11000, Mexico.
Addy Cecilia Helguera-RepettoDepartamento de Inmunobioquímica, Instituto Nacional de Perinatología (INPer), Mexico City 11000, Mexico.
Óscar Villavicencio-CarrisozaDepartamento de Inmunobioquímica, Instituto Nacional de Perinatología (INPer), Mexico City 11000, Mexico.
María Yolotzin Valdespino-VazquezDepartamento de Anatomía Patológica, INPer, Mexico City 11000, Mexico.
Arturo Flores-PliegoDepartamento de Inmunobioquímica, Instituto Nacional de Perinatología (INPer), Mexico City 11000, Mexico.ORCID 0000-0001-7876-6098
Claudine IrlesDepartamento de Fisiología y Desarrollo Celular, INPer, Mexico City 11000, Mexico.
Bruno Rivas-SantiagoUnidad de Investigación Médica IMSS Zacatecas, Zacatecas 98000, Mexico.
Elsa Romelia Moreno-VerduzcoSubdirección de Auxiliares de Diagnóstico, INPer, Mexico City 11000, Mexico.
Lorenza DíazDepartamento de Biología de la Reproducción, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City 14080, Mexico.ORCID 0000-0002-5947-4222
Verónica Zaga-ClavellinaDepartamento de Fisiología y Desarrollo Celular, INPer, Mexico City 11000, Mexico.ORCID 0000-0002-3365-2932
Instituto Nacional de Perinatología · MXInstituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán · MXUniversidad Autónoma de Zacatecas "Francisco García Salinas" · MX

Funding

Consejo Nacional de Ciencia y Tecnología 212250-3210-21205-01-15Consejo Nacional de Ciencia y Tecnología CB-242162
6 · The paper itself

Abstract

An infectious process into the uterine cavity represents a major endangered condition that compromises the immune privilege of the maternal-fetal unit and increases the risk for preterm birth (PTB) and premature rupture of membranes (PROM). Fetal membranes are active secretors of antimicrobial peptides (AMP), which limit bacterial growth, such as

Indexed as

beta-DefensinsEscherichia coli InfectionsPremature BirthEscherichia coliExtraembryonic MembranesFemaleHumansImmunity, InnateInfant, NewbornPregnancybeta-Defensinsalpha defensinsantimicrobial peptidesbeta defensinscollagen degradationgenitourinary infectioninnate defenseinnate immunitymaternal–fetal interface

Identifiers

PMID35328414
PMCPMC8949057
OpenAlexW4220664535

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.