Evidence map›Paper›PMID 35328344›Full record

ArticleInternational journal of molecular sciences2022

Active nNOS Is Required for Grp94-Induced Antioxidant Cytoprotection: A Lesson from Myogenic to Cancer Cells.

Filippo Fornasiero, Cristina Scapin, Maurizio Vitadello, Paola Pizzo, Luisa Gorza

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Filippo FornasieroDepartment of Biomedical Sciences, University of Padova, 35131 Padova, Italy.
Cristina ScapinDepartment of Biomedical Sciences, University of Padova, 35131 Padova, Italy.
Maurizio VitadelloCNR-Neuroscience Institute, National Research Council, 35131 Padova, Italy.
Paola PizzoDepartment of Biomedical Sciences, University of Padova, 35131 Padova, Italy.ORCID 0000-0001-6077-3265
Luisa GorzaDepartment of Biomedical Sciences, University of Padova, 35131 Padova, Italy.ORCID 0000-0003-4897-400X
University of Padua · ITNeuroscience Institute · IT

Funding

Italian Ministry of University and Scientific Research PRIN2017XA5J5NUniversity of Padova DOR 2017 and SID2019
6 · The paper itself

Abstract

The endoplasmic reticulum (ER) chaperone Grp94/gp96 appears to be involved in cytoprotection without being required for cell survival. This study compared the effects of Grp94 protein levels on Ca

Indexed as

Breast NeoplasmsCytoprotectionAntioxidantsCell LineEndoplasmic ReticulumFemaleHumansAntioxidantsC2C12 cell linecalciumendoplasmic reticulumgp96Grp94MDA-MB-231 cell linenNOSoxidative stressPMCASERCA2

Identifiers

PMID35328344
PMCPMC8954037
OpenAlexW4221026272

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.