Evidence map›Paper›PMID 35328324›Full record

ArticleInternational journal of molecular sciences2022

Bladder Cancer Extracellular Vesicles Elicit a CD8 T Cell-Mediated Antitumor Immunity.

Carlos J Ortiz-Bonilla, Taylor P Uccello, Scott A Gerber, Edith M Lord, Edward M Messing, Yi-Fen Lee

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. The role of exosomes in bladder cancer immunotherapy.Journal of the National Cancer Center · 2025
    Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Carlos J Ortiz-BonillaDepartment of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, NY 14642, USA.ORCID 0000-0002-6949-6193
Taylor P UccelloDepartment of Immunology, Microbiology and Virology, University of Rochester Medical Center, Rochester, NY 14642, USA.ORCID 0000-0002-3186-1319
Scott A GerberDepartment of Immunology, Microbiology and Virology, University of Rochester Medical Center, Rochester, NY 14642, USA.
Edith M LordDepartment of Immunology, Microbiology and Virology, University of Rochester Medical Center, Rochester, NY 14642, USA.
Edward M MessingWilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY 14642, USA.
Yi-Fen LeeDepartment of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, NY 14642, USA.
University of Rochester Medical Center · US

Funding

The T32 Predoctoral Training Program in Immunology (PTPI)T32AI007285 · NIAID · UNIVERSITY OF ROCHESTER · PI Scott Andrew Gerber, JACQUES Robert · 1986 to 2026
$7.6M
NIAID NIH HHS T32 AI007285
6 · The paper itself

Abstract

Tumor-derived extracellular vesicles (TEVs) play crucial roles in mediating immune responses, as they carry and present functional MHC-peptide complexes that enable them to modulate antigen-specific CD8

Indexed as

Extracellular VesiclesUrinary Bladder NeoplasmsAnimalsCD8-Positive T-LymphocytesCell Line, TumorHumansImmunity, CellularMiceMice, Inbred C57BLadjuvant therapybladder cancerCD8+ T cellextracellular vesiclesimmunotherapy

Identifiers

PMID35328324
PMCPMC8949613
OpenAlexW4221018212

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.