Evidence map›Paper›PMID 35328234›Full record

ArticleDiagnostics (Basel, Switzerland)2022

The Role of Nuclear Medicine Imaging with

Ramune Aleksyniene, Victor Iyer, Henrik Christian Bertelsen, Majbritt Frost Nilsson, Vesal Khalid, Henrik Carl Schønheyder, Lone Heimann Larsen, Poul Torben Nielsen, Andreas Kappel, Trine Rolighed Thomsen and 5 more

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. SimultaneousInternational orthopaedics · 2022
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 2 countries.

Ramune AleksynieneDepartment of Nuclear Medicine, Aalborg University Hospital, 9000 Aalborg, Denmark.
Victor IyerDepartment of Nuclear Medicine, Aalborg University Hospital, 9000 Aalborg, Denmark.
Henrik Christian BertelsenDepartment of Nuclear Medicine, Aalborg University Hospital, 9000 Aalborg, Denmark.
Majbritt Frost NilssonDepartment of Nuclear Medicine, Aalborg University Hospital, 9000 Aalborg, Denmark.ORCID 0000-0001-9682-4829
Vesal KhalidDepartment of Clinical Medicine, Aalborg University, 9220 Aalborg, Denmark.ORCID 0000-0001-5507-0645
Henrik Carl SchønheyderDepartment of Clinical Microbiology, Aalborg University Hospital, 9000 Aalborg, Denmark.
Lone Heimann LarsenDepartment of Clinical Microbiology, Aalborg University Hospital, 9000 Aalborg, Denmark.
Poul Torben NielsenInterdisciplinary Orthopaedics, Department of Orthopaedic Surgery, Aalborg University Hospital, 9000 Aalborg, Denmark.
Andreas KappelInterdisciplinary Orthopaedics, Department of Orthopaedic Surgery, Aalborg University Hospital, 9000 Aalborg, Denmark.
Trine Rolighed ThomsenCenter for Microbial Communities, Aalborg University, 9220 Aalborg, Denmark.
Jan LorenzenDanish Technology Institute, Medical Biotechnology, 8000 Aarhus, Denmark.
Iben ØrstedDepartment of Infectious Diseases, Aalborg University Hospital, 9000 Aalborg, Denmark.
Ole SimonsenInterdisciplinary Orthopaedics, Department of Orthopaedic Surgery, Aalborg University Hospital, 9000 Aalborg, Denmark.
Peter Lüttge JordalDanish Technology Institute, Medical Biotechnology, 8000 Aarhus, Denmark.
Sten RasmussenDepartment of Clinical Medicine, Aalborg University, 9220 Aalborg, Denmark.ORCID 0000-0002-8664-352X
Aalborg University Hospital · DKDanish Technological Institute · DKUppsala University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this prospective study was to assess the diagnostic value of nuclear imaging with MATERIALS AND

methodsFifty-five patients underwent imaging with

resultsThe diagnostic performance of dual-isotope WBC/bone marrow SPECT/CT for PJI showed a sensitivity of 100% (CI 0.74-1.00), a specificity of 97% (CI 0.82-1.00), and an accuracy of 98% (CI 0.88-1.00); for PET/CT, the sensitivity, specificity, and accuracy were 100% (CI 0.74-1.00), 71% (CI 0.56-0.90), and 79% (CI 0.68-0.93), respectively.

conclusionsIn a standardized prospectively scheduled patient group, the results showed highly specific performance of combined dual-isotope WBC/bone marrow SPECT/CT in confirming chronic PJI. FDG PET/CT has an appropriate accuracy, but the utility of its use in the clinical diagnostic algorithm of suspected PJI needs further evidence.

Indexed as

bone scandual-isotope WBC/bone marrow scanFDG PET/CThybrid imaginglabeled leucocyte imagingnuclear imagingperiprosthetic infectionprosthetic joint infection

Identifiers

PMID35328234
PMCPMC8947521
OpenAlexW4220970292

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.