Evidence map›Paper›PMID 35328188›Full record

ArticleDiagnostics (Basel, Switzerland)2022

Posterior Fossa Tumours in the First Year of Life: A Two-Centre Retrospective Study.

Stefania Picariello, Pietro Spennato, Jonathan Roth, Nir Shimony, Alessandra Marini, Lucia De Martino, Giancarlo Nicosia, Giuseppe Mirone, Maria Serena De Santi, Fabio Savoia and 4 more

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Stefania PicarielloNeuro-Oncology Unit, Department of Paediatric Oncology, Santobono-Pausilipon Children's Hospital, Via Mario Fiore 6, 80129 Naples, Italy.
Pietro SpennatoDivision of Neurosurgery, Department of Neurosciences, Santobono-Pausilipon Children's Hospital, Via Mario Fiore 6, 80129 Naples, Italy.ORCID 0000-0001-7758-8605
Jonathan RothDepartments of Pediatric Neurosurgery, Dana Children's Hospital, Tel Aviv Medical Center, Tel Aviv University, 6 Weizmann St., Tel Aviv 6423906, Israel.
Nir ShimonyDepartments of Pediatric Neurosurgery, Dana Children's Hospital, Tel Aviv Medical Center, Tel Aviv University, 6 Weizmann St., Tel Aviv 6423906, Israel.ORCID 0000-0002-7930-8782
Alessandra MariniDepartment of Neurosurgery, Ospedale Santa Maria della Misericordia di Perugia, Piazzale Giorgio Menghini 3, 06129 Perugia, Italy.
Lucia De MartinoNeuro-Oncology Unit, Department of Paediatric Oncology, Santobono-Pausilipon Children's Hospital, Via Mario Fiore 6, 80129 Naples, Italy.
Giancarlo NicosiaNeurosurgery Unit, San Pio Hospital, Via Pacevecchia 53, 82100 Benevento, Italy.
Giuseppe MironeDivision of Neurosurgery, Department of Neurosciences, Santobono-Pausilipon Children's Hospital, Via Mario Fiore 6, 80129 Naples, Italy.
Maria Serena De SantiDivision of Neurosurgery, Department of Neurosciences, Santobono-Pausilipon Children's Hospital, Via Mario Fiore 6, 80129 Naples, Italy.
Fabio SavoiaChildhood Cancer Registry of Campania, Santobono-Pausilipon Children's Hospital, Via della Croce Rossa 8, 80129 Naples, Italy.
Maria Elena ErricoDepartment of Pathology, Santobono-Pausilipon Children's Hospital, Via Posillipo 226, 80123 Naples, Italy.
Lucia QuagliettaNeuro-Oncology Unit, Department of Paediatric Oncology, Santobono-Pausilipon Children's Hospital, Via Mario Fiore 6, 80129 Naples, Italy.
Shlomi CostantiniDepartments of Pediatric Neurosurgery, Dana Children's Hospital, Tel Aviv Medical Center, Tel Aviv University, 6 Weizmann St., Tel Aviv 6423906, Israel.
Giuseppe CinalliDivision of Neurosurgery, Department of Neurosciences, Santobono-Pausilipon Children's Hospital, Via Mario Fiore 6, 80129 Naples, Italy.ORCID 0000-0002-7797-8483
Santobono Children's Hospital · ITTel Aviv University · ILOspedale Santa Maria · ITUniversity of Campania "Luigi Vanvitelli" · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Posterior fossa tumours (PFTs) in infants are very rare, and information on these tumours is scarce in the literature. This retrospective study reports their pathological characteristics and describes surgical aspects and treatment outcomes. A two-centre cohort of infants with PFTs treated from 2007 to 2018 was retrospectively reviewed. Patient characteristics, clinical, and treatment data were reviewed. Survival curves for progression-free survival (PFS) and overall survival (OS) were generated. Thirty-three infants were retrieved. There were 11 low grade and 22 high-grade tumours. The most common presenting symptom was intracranial hypertension. Fifteen children out of thirty-three progressed. Five-year PFS was significantly lower in children with high-grade tumours (38.3%) than those with low-grade tumours (69.3%),

Indexed as

astrocytomaAtypical Teratoid/Rhabdoid Tumourependymomainfantsinfratentorial tumoursmedulloblastomaposterior fossa tumours

Identifiers

PMID35328188
PMCPMC8947426
OpenAlexW4221013752

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.