Evidence map›Paper›PMID 35328142›Full record

ArticleDiagnostics (Basel, Switzerland)2022

Open-Source, Adaptable, All-in-One Smartphone-Based System for Quantitative Analysis of Point-of-Care Diagnostics.

Weronika Schary, Filip Paskali, Simone Rentschler, Christoph Ruppert, Gabriel E Wagner, Ivo Steinmetz, Hans-Peter Deigner, Matthias Kohl

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Weronika ScharyMedical and Life Sciences Faculty, Furtwangen University, 78054 Villingen-Schwenningen, Germany.ORCID 0000-0002-7229-316X
Filip PaskaliMedical and Life Sciences Faculty, Furtwangen University, 78054 Villingen-Schwenningen, Germany.ORCID 0000-0002-9647-6294
Simone RentschlerMedical and Life Sciences Faculty, Furtwangen University, 78054 Villingen-Schwenningen, Germany.ORCID 0000-0002-3158-3603
Christoph RuppertMedical and Life Sciences Faculty, Furtwangen University, 78054 Villingen-Schwenningen, Germany.
Gabriel E WagnerInstitute of Hygiene, Microbiology and Environmental Medicine, Medical University of Graz, 8010 Graz, Austria.ORCID 0000-0002-5704-3955
Ivo SteinmetzInstitute of Hygiene, Microbiology and Environmental Medicine, Medical University of Graz, 8010 Graz, Austria.ORCID 0000-0003-0510-7336
Hans-Peter DeignerMedical and Life Sciences Faculty, Furtwangen University, 78054 Villingen-Schwenningen, Germany.ORCID 0000-0002-7745-0152
Matthias KohlMedical and Life Sciences Faculty, Furtwangen University, 78054 Villingen-Schwenningen, Germany.ORCID 0000-0001-9514-8910

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Point-of-care (POC) diagnostics, in particular lateral flow assays (LFA), represent a great opportunity for rapid, precise, low-cost and accessible diagnosis of disease. Especially with the ongoing coronavirus disease 2019 (COVID-19) pandemic, rapid point-of-care tests are becoming everyday tools for identification and prevention. Using smartphones as biosensors can enhance POC devices as portable, low-cost platforms for healthcare and medicine, food and environmental monitoring, improving diagnosis and documentation in remote, low-resource locations. We present an open-source, all-in-one smartphone-based system for quantitative analysis of LFAs. It consists of a 3D-printed photo box, a smartphone for image acquisition, and an R Shiny software package with modular, customizable analysis workflow for image editing, analysis, data extraction, calibration and quantification of the assays. This system is less expensive than commonly used hardware and software, so it could prove very beneficial for diagnostic testing in the context of pandemics, as well as in low-resource countries.

Indexed as

lateral flow assayspoint-of-care diagnosticsquantitative image analysisR Shiny applicationsmartphone-based system

Identifiers

PMID35328142
PMCPMC8947044

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.