ReviewGenes2022
Mediterranean Diet and Genetic Determinants of Obesity and Metabolic Syndrome in European Children and Adolescents.
Review in Genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed, 22 citations in OpenAlex.
- Odds of Developing Overweight or Obesity Increase with Height Decile in Tall Healthy Weight Kindergarteners: Longitudinal Results from the West Virginia Coronary Artery Risk Detection In Appalachian Communities (WV CARDIAC) Project.Journal of pediatrics. Clinical practice · 2026Article
- FTO rs9939609 genotype and behavioral determinants of Mediterranean diet adherence in young women: exploratory insights into potential metabolic relevance.Frontiers in nutrition · 2026Article
- From cooperation to collapse: the diet-microbiota-host gene triad in disease and aging.Frontiers in microbiomes · 2026Review
- Gut Microbiota and Short-Chain Fatty Acids: Key Factors in Pediatric Obesity and Therapeutic Targets.International journal of molecular sciences · 2025Review
- Tracing the Path from Obesity to Diabetes: How S-Allyl Cysteine Shapes Metabolic Health.Nutrients · 2025Review
- Obesity genetic association prospective cohort utilizing single center real-world evidence data.Medicine · 2025Article
- Genetic architecture and mechanisms shared between kidney and ureteral stones, cardiovascular diseases, and metabolic syndrome: A comprehensive GWAS analysis.Biochemistry and biophysics reports · 2025Article
- Mediterranean diet and obesity polygenic risk interaction on adiposity in European children: The IDEFICS/I.Family Study.Pediatric obesity · 2025Article
- Association between Mediterranean diet and metabolic health status among adults was not mediated through serum adropin levels.BMC public health · 2025Observational
- Review
- Adherence to a healthy lifestyle behavior composite score and cardiometabolic risk factors in Spanish children from the CORALS cohort.European journal of pediatrics · 2024Article
- Metabolic syndrome therapy in pediatric age - between classic and modern. From diets to pipeline drugs.Frontiers in nutrition · 2024Review
- Polymorphisms of Fat Mass and Obesity-Associated Gene in the Pathogenesis of Child and Adolescent Metabolic Syndrome.Nutrients · 2023Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Childhood obesity and metabolic syndrome (MetS) are multifactorial diseases influenced by genetic and environmental factors. The Mediterranean Diet (MD) seems to modulate the genetic predisposition to obesity or MetS in European adults. The FTO gene has also been shown to have an impact on the MD benefits to avoid obesity or MetS. Since these interaction effects have been scarcely analyzed in European youth, the aim was to describe the gene-MD interplay, analyzing the impact of the genetic factors to reduce the obesity and MetS risk through MD adherence, and the MD impact in the obesity and MetS genetic profile. From the limited evidence on gene-MD interaction studies in European youth, a study showed that the influence of high MD adherence on adiposity and MetS was only observed with a limited number of risk alleles; the gene-MD interplay showed sex-specific differences, being higher in females. Most results analyzed in European adults elucidate that, the relationship between MD adherence and both obesity and MetS risk, could be modulated by obesity genetic variants and vice versa. Further research is needed, to better understand the inter-individual differences in the association between MD and body composition, and the integration of omics and personalized nutrition considering MD.
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Registered trials
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