Evidence map›Paper›PMID 35327741›Full record

ArticleChildren (Basel, Switzerland)2022

Safety of Monoclonal Antibodies in Children Affected by SARS-CoV-2 Infection.

Lorenza Romani, Francesca Ippolita Calò Carducci, Sara Chiurchiù, Laura Cursi, Maia De Luca, Martina Di Giuseppe, Andrzej Krzysztofiak, Laura Lancella, Paolo Palma, Leonardo Vallesi and 5 more

Open access · goldAbstract read
In one paragraph

Article in Children (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Observational
  7. SARS-CoV-2 infection and treatment in a cohort of patients with inborn errors of immunity.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2022
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Lorenza RomaniImmunology and Infectious Disease Unit, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Francesca Ippolita Calò CarducciImmunology and Infectious Disease Unit, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Sara ChiurchiùImmunology and Infectious Disease Unit, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Laura CursiImmunology and Infectious Disease Unit, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Maia De LucaImmunology and Infectious Disease Unit, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Martina Di GiuseppeImmunology and Infectious Disease Unit, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Andrzej KrzysztofiakImmunology and Infectious Disease Unit, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Laura LancellaImmunology and Infectious Disease Unit, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Paolo PalmaResearch Unit of Congenital and Perinatal Infections, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Leonardo VallesiHospital Pharmacy Unit, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Tiziana CorsettiHospital Pharmacy Unit, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Andrea CampanaDepartment of Pediatrics, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Emanuele NicastriNational Institute for Infectious Diseases, Lazzaro Spallanzani, IRCCS, 00149 Rome, Italy.
Paolo RossiChair of Pediatrics, Department of Systems Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.
Stefania BernardiImmunology and Infectious Disease Unit, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Bambino Gesù Children's Hospital · ITUniversity of Rome Tor Vergata · ITIstituto Nazionale per le Malattie Infettive Lazzaro Spallanzani · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Monoclonal antibody therapies for COVID-19 have been frequently used in adults, whereas there are little data regarding the safety or efficacy of monoclonal antibody treatments in pediatric patients affected by COVID-19. We report our experience in the administration of mAb as a treatment for SARS-CoV-2 infection in children aged from 24 days to 18 years old.

Indexed as

childrenCOVID-19monoclonal antibody

Identifiers

PMID35327741
PMCPMC8947030
OpenAlexW4220689559

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.