Evidence map›Paper›PMID 35327728›Full record

ReviewChildren (Basel, Switzerland)2022

Advanced Brain Imaging in Preterm Infants: A Narrative Review of Microstructural and Connectomic Disruption.

Philippe Vo Van, Marianne Alison, Baptiste Morel, Jonathan Beck, Nathalie Bednarek, Lucie Hertz-Pannier, Gauthier Loron

Abstract readReview
In one paragraph

Review in Children (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Early Marriage, Preterm Birth, and School Dropout: An Intergenerational Cycle of Risk?American journal of human biology : the official journal of the Human Biology Council · 2025
    Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Maturation of Neuronal Activity in the Human Cortex Exhibits Robust Spatial Gradients across the Birth Transition.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  7. Temporal complexity of the BOLD-signal in preterm versus term infants.Cerebral cortex (New York, N.Y. : 1991) · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Philippe Vo VanDepartment of Neonatology, Hospices Civils de Lyon, Femme Mère Enfant Hospital, 59 Boulevard Pinel, 69500 Bron, France.ORCID 0000-0003-0654-2874
Marianne AlisonService d'Imagerie Pédiatrique, Hôpital Robert Debré, APHP, 75019 Paris, France.
Baptiste MorelPediatric Radiology Department, Clocheville Hospital, CHRU of Tours, 37000 Tours, France.
Jonathan BeckDepartment of Neonatology, Reims University Hospital Alix de Champagne, 51100 Reims, France.ORCID 0000-0001-9456-2984
Nathalie BednarekDepartment of Neonatology, Reims University Hospital Alix de Champagne, 51100 Reims, France.
Lucie Hertz-PannierU1141 Neurodiderot, Équipe 5 inDev, Inserm, CEA, Université de Paris, 75019 Paris, France.
Gauthier LoronDepartment of Neonatology, Reims University Hospital Alix de Champagne, 51100 Reims, France.ORCID 0000-0001-9536-9510

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Preterm birth disrupts the in utero environment, preventing the brain from fully developing, thereby causing later cognitive and behavioral disorders. Such cerebral alteration occurs beneath an anatomical scale, and is therefore undetectable by conventional imagery. Prematurity impairs the microstructure and thus the histological process responsible for the maturation, including the myelination. Cerebral MRI diffusion tensor imaging sequences, based on water's motion into the brain, allows a representation of this maturation process. Similarly, the brain's connections become disorganized. The connectome gathers structural and anatomical white matter fibers, as well as functional networks referring to remote brain regions connected one over another. Structural and functional connectivity is illustrated by tractography and functional MRI, respectively. Their organizations consist of core nodes connected by edges. This basic distribution is already established in the fetal brain. It evolves greatly over time but is compromised by prematurity. Finally, cerebral plasticity is nurtured by a lifetime experience at microstructural and macrostructural scales. A preterm birth causes a negative and early disruption, though it can be partly mitigated by positive stimuli based on developmental neonatal care.

Indexed as

connectivitymicrostructureMRIpreterm infants

Identifiers

PMID35327728
PMCPMC8947160

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.