Evidence map›Paper›PMID 35327724›Full record

ArticleChildren (Basel, Switzerland)2022

Relationship between Admission Temperature and Risk of Cerebral Palsy in Infants Admitted to Special Care Unit in a Low Resource Setting: A Retrospective Single-Center Study.

Chiara Guadagno, Francesco Cavallin, Luca Brasili, Donald Micah Maziku, Dionis Erasto Leluko, Gaetano Azzimonti, Giovanni Putoto, Andrea Pietravalle, Daniele Trevisanuto

Open access · goldAbstract read
In one paragraph

Article in Children (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Chiara GuadagnoDoctors with Africa CUAMM, Dar es Salaam 23447, Tanzania.ORCID 0000-0003-4059-5443
Francesco CavallinIndependent Statistician, 36020 Solagna, Italy.ORCID 0000-0002-0831-3971
Luca BrasiliDoctors with Africa CUAMM, Dar es Salaam 23447, Tanzania.
Donald Micah MazikuSt. John of the Cross, Tosamaganga Council Designated Hospital, Tosamaganga 51201, Tanzania.
Dionis Erasto LelukoSt. John of the Cross, Tosamaganga Council Designated Hospital, Tosamaganga 51201, Tanzania.
Gaetano AzzimontiDoctors with Africa CUAMM, Dar es Salaam 23447, Tanzania.
Giovanni PutotoDoctors with Africa CUAMM, 35121 Padua, Italy.ORCID 0000-0003-0256-1744
Andrea PietravalleDoctors with Africa CUAMM, 35121 Padua, Italy.
Daniele TrevisanutoDepartment of Woman's and Child's Health, University of Padua, 35128 Padua, Italy.ORCID 0000-0002-6462-0079
Doctors with Africa Cuamm · ITTanzania National Parks · TZIstituto Nazionale di Statistica · ITUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDeviations from normothermia affect early mortality and morbidity, but the impact on neurodevelopment of the survivors is unclear. We aimed to investigate the relationship between neonatal temperature at admission and the risk of cerebral palsy (CP) at one month of age in a low-resource setting.

methodsThis retrospective study included all inborn neonates admitted to the Special Care Unit of Tosamaganga Hospital (Tanzania) between 1 January 2019 and 31 December 2020. The neurological examination at one month of age was performed using the Hammersmith method. The relationship between the admission temperature and the risk of CP was investigated using logistic regression models, with temperature modeled as the non-linear term.

resultsHigh/moderate risk of CP was found in 40/119 (33.6%) of the neonates at one month of age. A non-linear relationship between the admission temperature and moderate/high risk of CP at one month of age was found. The lowest probability of moderate/high risk of CP was estimated at admission temperatures of between 35 and 36 °C, with increasing probability when departing from such temperatures.

conclusionsIn a low-resource setting, we found a U-shaped relationship between the admission temperature and the risk of CP at one month of life. Expanding the analysis of the follow-up data to 12-24 months of age would be desirable in order to confirm and strengthen such findings.

Indexed as

birthcerebral palsyhypothermialow-resource settingneonateneurological outcometemperature

Identifiers

PMID35327724
PMCPMC8947039
OpenAlexW4214824877

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.