ArticleChildren (Basel, Switzerland)2022
Salivary Enzymatic Activity and Carious Experience in Children: A Cross-Sectional Study.
Article in Children (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 9 citations in OpenAlex.
- Trial
- Oral health status in children with black tooth stain.BMC oral health · 2026Article
- Changes in Salivary Matrix Metalloproteinase-8 Concentrations Are Not Associated with Oral Health during Early Adolescence.Caries research · 2025Article
- Caries status influence GCF MMP-9 in association with serum vitamin D: an exploratory retrospective cross-sectional study.BMC oral health · 2025Article
- Perspectives on Matrix Metalloproteinase-8 and Salivary Osteoprotegerin in Orthodontic Strategy in Children with Chronic Kidney Disease.Journal of clinical medicine · 2025Article
- Salivary alpha-amylase activity and its association with early childhood caries and rampant caries experience: a cross-sectional study.Frontiers in medicine · 2024Article
- Article
- Study on the Influence of Regular Physical Activity on Children's Oral Health.Children (Basel, Switzerland) · 2023Article
- The Effect of Dental Treatments in Caries Management on Stress and Salivary Protein Levels.Journal of clinical medicine · 2022Article
- Salivary Assessments in Post-Liver Transplantation Patients.Journal of clinical medicine · 2022Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
Abstract
Salivary biomolecules are considered important modulators of the oral microflora, with a potential subsequent impact on dental health. The present study aimed to investigate the relationship between salivary enzymatic activity and carious experience in children. The carious experience of a sample of 22 school children was evaluated by calculating dmf/DMF indices, following WHO recommendations. Unstimulated whole saliva was collected, and salivary alpha-amylase levels, total protease activity, and matrix metalloproteinase levels (MMP-8 and MMP-9) were measured. The data were analyzed using parametric and nonparametric tests. Our findings revealed no significant relationship between the investigated salivary parameters and the carious experience in permanent teeth (DMFT/DMFS scores). Carious indices scores for primary teeth (dmft and dmfs) were positively associated with MMP-8 levels (
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Registered trials
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