Evidence map›Paper›PMID 35327684›Full record

ReviewChildren (Basel, Switzerland)2022

Neonatal Outcome and Treatment Perspectives of Preterm Infants at the Border of Viability.

Rahel Schuler, Ivonne Bedei, Frank Oehmke, Klaus-Peter Zimmer, Harald Ehrhardt

Abstract readReview
In one paragraph

Review in Children (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Prevalence of congenital anomalies in newborns: a cross-sectional study in the state of Rio de Janeiro, Brazil, 2019-2021.Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil · 2025
    Article
  6. Review
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rahel SchulerDepartment of General Pediatrics and Neonatology, Justus-Liebig-University, Feulgenstrasse 12, 35392 Giessen, Germany.
Ivonne BedeiDepartment of Obstetrics and Gynecology, Justus-Liebig-University, Klinikstrasse 33, 35392 Giessen, Germany.ORCID 0000-0002-7688-5357
Frank OehmkeDepartment of Obstetrics and Gynecology, Justus-Liebig-University, Klinikstrasse 33, 35392 Giessen, Germany.
Klaus-Peter ZimmerDepartment of General Pediatrics and Neonatology, Justus-Liebig-University, Feulgenstrasse 12, 35392 Giessen, Germany.
Harald EhrhardtDepartment of General Pediatrics and Neonatology, Justus-Liebig-University, Feulgenstrasse 12, 35392 Giessen, Germany.ORCID 0000-0003-4587-1734

Funding

Nestlé (Germany) no numberStephan no number
6 · The paper itself

Abstract

Decision-making at the border of viability remains challenging for the expectant parents and the medical team. The preterm infant is dependent on others making the decision that will impact them for a lifetime in hopefully their best interest. Besides survival and survival without neurodevelopmental impairment, other relevant outcome measures, such as the quality of life of former preterm infants and the impact on family life, need to be integrated into prenatal counselling. Recommendations and national guidelines continue to rely on arbitrarily set gestational age limits at which treatment is not recommended, can be considered and it is recommended. These guidelines neglect other individual prognostic outcome factors like antenatal steroids, birth weight and gender. Besides individual factors, centre-specific factors like perinatal treatment intensity and the attitude of healthcare professionals significantly determine the futures of these infants at the border of viability. A more comprehensive approach regarding treatment recommendations and relevant outcome measures is necessary.

Indexed as

border of viabilitydecision-makingextremely preterm infantoutcome measuresquality of lifesurvivalsurvival without disability

Identifiers

PMID35327684
PMCPMC8946876

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.