Evidence map›Paper›PMID 35327451›Full record

ArticleBiomedicines2022

The Antiplatelet Action of S-Nitroso Human Serum Albumin in Whole Blood.

Melina Tsiountsioura, Gerhard Cvirn, Axel Schlagenhauf, Harald Haidl, Kathrin Zischmeier, Nicole Janschitz, Martin Koestenberger, Willibald Wonisch, Margret Paar, Thomas Wagner and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Melina TsiountsiouraDivision of Physiological Chemistry, Otto Loewi Research Center, Medical University of Graz, 8010 Graz, Austria.
Gerhard CvirnDivision of Physiological Chemistry, Otto Loewi Research Center, Medical University of Graz, 8010 Graz, Austria.ORCID 0000-0002-1410-1844
Axel SchlagenhaufDivision of General Paediatrics, Department of Paediatrics and Adolescent Medicine, Medical University of Graz, 8036 Graz, Austria.
Harald HaidlDivision of General Paediatrics, Department of Paediatrics and Adolescent Medicine, Medical University of Graz, 8036 Graz, Austria.
Kathrin ZischmeierDepartment of Pharmacology and Toxicology, University of Graz, 8010 Graz, Austria.
Nicole JanschitzDepartment of Pharmacology and Toxicology, University of Graz, 8010 Graz, Austria.
Martin KoestenbergerDivision of General Paediatrics, Department of Paediatrics and Adolescent Medicine, Medical University of Graz, 8036 Graz, Austria.ORCID 0000-0003-1766-7859
Willibald WonischDivision of Physiological Chemistry, Otto Loewi Research Center, Medical University of Graz, 8010 Graz, Austria.ORCID 0000-0001-7171-9539
Margret PaarDivision of Physiological Chemistry, Otto Loewi Research Center, Medical University of Graz, 8010 Graz, Austria.ORCID 0000-0001-5494-8890
Thomas WagnerDepartment of Blood Group Serology and Transfusion Medicine, Medical University of Graz, 8036 Graz, Austria.
Eva-Christine WeissDepartment of Obstetrics and Gynecology, Medical University of Graz, 8036 Graz, Austria.
Seth HallströmDivision of Physiological Chemistry, Otto Loewi Research Center, Medical University of Graz, 8010 Graz, Austria.
Medical University of Graz · ATUniversity of Graz · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nitric oxide donors (NO-donors) have been shown to have therapeutic potential (e.g., ischemia/reperfusion injury). However, due to their release rate/antiplatelet properties, they may cause bleeding in patients. We therefore studied the antiplatelet effects of the two different NO-donors, i.e., S-NO-Human Serum Albumin (S-NO-HSA) and Diethylammonium (Z)-1-(

Indexed as

impedance aggregometrynitric oxide donorsplatelet function

Identifiers

PMID35327451
PMCPMC8945101
OpenAlexW4220874664

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.