Evidence map›Paper›PMID 35327348›Full record

ArticleBiomedicines2022

Artificial Intelligence for Risk Prediction of End-Stage Renal Disease in Sepsis Survivors with Chronic Kidney Disease.

Kuo-Hua Lee, Yuan-Chia Chu, Ming-Tsun Tsai, Wei-Cheng Tseng, Yao-Ping Lin, Shuo-Ming Ou, Der-Cherng Tarng

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Kuo-Hua LeeDivision of Nephrology, Department of Medicine, Taipei Veterans General Hospital, Taipei 11217, Taiwan.
Yuan-Chia ChuInformation Management Office, Taipei Veterans General Hospital, Taipei 11217, Taiwan.
Ming-Tsun TsaiDivision of Nephrology, Department of Medicine, Taipei Veterans General Hospital, Taipei 11217, Taiwan.ORCID 0000-0002-8597-4132
Wei-Cheng TsengDivision of Nephrology, Department of Medicine, Taipei Veterans General Hospital, Taipei 11217, Taiwan.ORCID 0000-0002-6940-9651
Yao-Ping LinDivision of Nephrology, Department of Medicine, Taipei Veterans General Hospital, Taipei 11217, Taiwan.
Shuo-Ming OuDivision of Nephrology, Department of Medicine, Taipei Veterans General Hospital, Taipei 11217, Taiwan.
Der-Cherng TarngDivision of Nephrology, Department of Medicine, Taipei Veterans General Hospital, Taipei 11217, Taiwan.ORCID 0000-0001-9017-2081
National Yang Ming Chiao Tung University · TWTaipei Veterans General Hospital · TW

Funding

Ministry of Science and Technology 108-2314-B-075-008, 109-2314-B-075 -067 -MY3, 109-2314-B-010-056-MY3, 109-2314-B-075-066, 110-2314-B-075-008Taipei Veterans General Hospital V109D50-001-MY3-1, V109D50-001-MY3-2, V109C-114, V109B-016, V109B-022, V110C-152, V110E-003-2, V110B-030Taiwan Poison Control FPC-110-003
6 · The paper itself

Abstract

Sepsis may lead to kidney function decline in patients with chronic kidney disease (CKD), and the deleterious effect may persist in patients who survive sepsis. We used a machine learning approach to predict the risk of end-stage renal disease (ESRD) in sepsis survivors. A total of 11,661 sepsis survivors were identified from a single-center database of 112,628 CKD patients between 2010 and 2018. During a median follow-up of 3.5 years, a total of 1366 (11.7%) sepsis survivors developed ESRD after hospital discharge. We adopted the random forest, extra trees, extreme gradient boosting, light gradient boosting machine (LGBM), and gradient boosting decision tree (GBDT) algorithms to predict the risk of ESRD development among these patients. GBDT yielded the highest area under the receiver operating characteristic curve of 0.879, followed by LGBM (0.868), and extra trees (0.865). The GBDT model revealed the strong effect of estimated glomerular filtration rates <25 mL/min/1.73 m2 at discharge in predicting ESRD development. In addition, hemoglobin and proteinuria were also essential predictors. Based on a large-scale dataset, we established a machine learning model computing the risk for ESRD occurrence among sepsis survivors with CKD. External validation is required to evaluate the generalizability of this model.

Indexed as

artificial intelligencechronic kidney diseaseend-stage renal diseasemachine learningsepsis

Identifiers

PMID35327348
PMCPMC8945427
OpenAlexW4214664378

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.