Evidence map›Paper›PMID 35327191›Full record

ArticleAnimals : an open access journal from MDPI2022

Effects of Environmental Heat Load on Endocannabinoid System Components in Adipose Tissue of High Yielding Dairy Cows.

Gitit Kra, Jayasimha Rayalu Daddam, Uzi Moallem, Hadar Kamer, Majdoleen Ahmad, Alina Nemirovski, G Andres Contreras, Joseph Tam, Maya Zachut

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Gitit KraDepartment of Ruminant Science, Institute of Animal Sciences, Agriculture Research Organization, Volcani Institute, Rishon Lezion 7505101, Israel.
Jayasimha Rayalu DaddamDepartment of Ruminant Science, Institute of Animal Sciences, Agriculture Research Organization, Volcani Institute, Rishon Lezion 7505101, Israel.ORCID 0000-0002-0666-8517
Uzi MoallemDepartment of Ruminant Science, Institute of Animal Sciences, Agriculture Research Organization, Volcani Institute, Rishon Lezion 7505101, Israel.
Hadar KamerDepartment of Ruminant Science, Institute of Animal Sciences, Agriculture Research Organization, Volcani Institute, Rishon Lezion 7505101, Israel.
Majdoleen AhmadObesity and Metabolism Laboratory, Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 9112001, Israel.
Alina NemirovskiObesity and Metabolism Laboratory, Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 9112001, Israel.
G Andres ContrerasDepartment of Large Animal Clinical Sciences, Michigan State University, East Lansing, MI 48824, USA.
Joseph TamObesity and Metabolism Laboratory, Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 9112001, Israel.ORCID 0000-0002-0948-0093
Maya ZachutDepartment of Ruminant Science, Institute of Animal Sciences, Agriculture Research Organization, Volcani Institute, Rishon Lezion 7505101, Israel.ORCID 0000-0002-9644-6028
Agricultural Research Organization · ILHebrew University of Jerusalem · ILMichigan State University · US

Funding

BARD, The United States - Israel Binational Agricultural Research and Development Fund IS-5167-19Israeli Dairy Board 362-0580
6 · The paper itself

Abstract

Environmental heat load (HL) adversely affects the performance of dairy cows. The endocannabinoid system (ECS) regulates metabolism and the stress response, thus we hypothesized that HL may affect the ECS of dairy cows. Our objective was to determine the levels of endocannabinoids (eCBs) and gene and protein expressions of the ECS components in adipose tissue (AT) and plasma of early postpartum (PP) and late-lactation cows. In addition, we examined eCBs in milk, and studied the interaction of eCBs with bovine cannabinoids receptors CB1 and CB2. In the first experiment, plasma and AT were sampled from cows calving during summer (S,

Indexed as

2-AGadipose tissueAEACB1dairy cowsendocannabinoidsheat stressPPAR-αTRPV1

Identifiers

PMID35327191
PMCPMC8944798
OpenAlexW4220654082

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.