Evidence map›Paper›PMID 35327184›Full record

ArticleAnimals : an open access journal from MDPI2022

Comprehensive Analyses of Bone and Cartilage Transcriptomes Evince Ion Transport, Inflammation and Cartilage Development-Related Genes Involved in Chickens' Femoral Head Separation.

Iara Goldoni, Adriana Mércia Guaratini Ibelli, Lana Teixeira Fernandes, Jane de Oliveira Peixoto, Ludmila Mudri Hul, Maurício Egídio Cantão, João José de Simoni Gouveia, Mônica Corrêa Ledur

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Iara GoldoniPrograma de Pós-Graduação em Ciências Veterinárias, Universidade Estadual do Centro-Oeste, R. Salvatore Renna, 875, Guarapuava 85015-430, PR, Brazil.
Adriana Mércia Guaratini IbelliPrograma de Pós-Graduação em Ciências Veterinárias, Universidade Estadual do Centro-Oeste, R. Salvatore Renna, 875, Guarapuava 85015-430, PR, Brazil.ORCID 0000-0003-0626-8879
Lana Teixeira FernandesEmbrapa Suínos e Aves, Rodovia BR 153, km 110, Concórdia 89715-899, SC, Brazil.
Jane de Oliveira PeixotoPrograma de Pós-Graduação em Ciências Veterinárias, Universidade Estadual do Centro-Oeste, R. Salvatore Renna, 875, Guarapuava 85015-430, PR, Brazil.
Ludmila Mudri HulPrograma de Pós-Graduação em Ciências Veterinárias, Universidade Estadual do Centro-Oeste, R. Salvatore Renna, 875, Guarapuava 85015-430, PR, Brazil.
Maurício Egídio CantãoEmbrapa Suínos e Aves, Rodovia BR 153, km 110, Concórdia 89715-899, SC, Brazil.
João José de Simoni GouveiaPrograma de Pós-Graduação em Ciências Veterinárias no Semiárido, Universidade Federal do Vale do São Francisco, UNIVASF, Rodovia BR 407, 12 Lote 543, Petrolina 56300-000, PE, Brazil.ORCID 0000-0002-0438-094X
Mônica Corrêa LedurEmbrapa Suínos e Aves, Rodovia BR 153, km 110, Concórdia 89715-899, SC, Brazil.ORCID 0000-0002-2645-4735
Concordia University Wisconsin · USUniversidade Estadual do Centro-Oeste · BRUniversidade Federal do Vale do São Francisco · BR

Funding

Brazilian Agricultural Research Corporation 01.11.07.002.04.03
6 · The paper itself

Abstract

Femoral head separation (FHS) is usually a subclinical condition characterized by the detachment of articular cartilage from the bone. In this study, a comprehensive analysis identifying shared and exclusive expression profiles, biological processes (BP) and variants related to FHS in the femoral articular cartilage and growth plate in chickens was performed through RNA sequencing analysis. Thirty-six differentially expressed (DE) genes were shared between femoral articular cartilage (AC) and growth plate (GP) tissues. Out of those, 23 genes were enriched in BP related to ion transport, translation factors and immune response. Seventy genes were DE exclusively in the AC and 288 in the GP. Among the BP of AC, the response against bacteria can be highlighted, and for the GP tissue, the processes related to chondrocyte differentiation and cartilage development stand out. When the chicken DE genes were compared to other datasets, eight genes (

Indexed as

femoral head necrosisgene expressioninflammatory responseintegrated analysisSNPs

Identifiers

PMID35327184
PMCPMC8944783
OpenAlexW4220953758

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.