ReviewAnimals : an open access journal from MDPI2022
Potential Role of Protocatechuic Acid as Natural Feed Additives in Farm Animal Production.
Review in Animals : an open access journal from MDPI, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 23 citations in OpenAlex.
- Review
- A Comprehensive Review on the Pharmacological Activities and Biosynthetic Strategies of Protocatechuic Acid.Life (Basel, Switzerland) · 2026Review
- Influence of black garlic and Hypericum scabrum on growth performance, fecal microbiota, diarrhea, oxidative stress and immune status in pre-weaning calves.Tropical animal health and production · 2026Article
- Synergistic effects ofVeterinary world · 2026Article
- Research on the process of synergistic degradation of corn straw by probiotics-enzymes based on microbiome and metabolomics.BMC microbiology · 2026Article
- Anthelmintic Activity of Protocatechuic Acid Against Ivermectin-Susceptible and ResistantPathogens (Basel, Switzerland) · 2026Article
- Article
- Functional Feed for Tilapia: Exploring the Benefits ofBiology · 2025Article
- Updated Review on Natural Polyphenols: Molecular Mechanisms, Biological Effects, and Clinical Applications for Cancer Management.Biomolecules · 2025Review
- Transcriptomic and proteomic analysis of the jejunum revealed the effects and mechanism of protocatechuic acid on alleviating Salmonella typhimurium infection in chickens.Poultry science · 2025Article
- Effects of Flavonoids inAntioxidants (Basel, Switzerland) · 2024Article
- Flavonols and Flavones as Potential anti-Inflammatory, Antioxidant, and Antibacterial Compounds.Oxidative medicine and cellular longevity · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Restriction on using antibiotics in animal feed that generates demand for antibiotics alternatives in animal breeding. Providing safe food to humans free from the residual effects of antibiotics is a great challenge to animal producers and food-producing industry owners. Medicinal plants and their extracts as feed supplements have been used to promote the growth and health of farm animals for centuries. Protocatechuic acid (PCA) is a phenolic compound that originated from natural plants. For years, the health-promoting role of PCA has been becoming an attraction of research in nutrition and pharmacy. Thus, it can be used as an active natural feed additive while synthetic antibiotics are illegal to use in animal breeding. However, the practical application of PCA in view of dosages in animal nutrition, together with its mode of action on animal health, is not well known. In this regard, this review study has explored the mode of action of PCA and the feasibility of using those compounds in animal nutrition. This review study concludes that phenolic-rich protocatechuic acid as a natural feed additive may be useful in enhancing antioxidant status, immune function, antimicrobial, intestinal health and growth performance of farm animals.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.