Evidence map›Paper›PMID 35327050›Full record

ArticleHealthcare (Basel, Switzerland)2022

Effect of Online Home-Based Training on Functional Capacity and Strength in Two CKD Patients: A Case Study.

Giulia Marrone, Elisa Grazioli, Eliana Tranchita, Attilio Parisi, Claudia Cerulli, Arianna Murri, Carlo Minganti, Manuela Di Lauro, Nicolò Piacentini, Leonarda Galiuto and 2 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Healthcare (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Giulia MarroneUOC of Internal Medicine-Center of Hypertension and Nephrology Unit, Department of Systems Medicine, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.ORCID 0000-0002-5854-2086
Elisa GrazioliDepartment of Experimental and Clinical Medicine, "Magna Graecia" University, 88100 Catanzaro, Italy.ORCID 0000-0003-4245-1320
Eliana TranchitaDepartment of Human, Movement Sciences and Health, University of Rome "Foro Italico", 00135 Rome, Italy.
Attilio ParisiDepartment of Human, Movement Sciences and Health, University of Rome "Foro Italico", 00135 Rome, Italy.ORCID 0000-0003-2648-8406
Claudia CerulliDepartment of Human, Movement Sciences and Health, University of Rome "Foro Italico", 00135 Rome, Italy.ORCID 0000-0003-2637-7968
Arianna MurriDepartment of Human, Movement Sciences and Health, University of Rome "Foro Italico", 00135 Rome, Italy.
Carlo MingantiDepartment of Human, Movement Sciences and Health, University of Rome "Foro Italico", 00135 Rome, Italy.
Manuela Di LauroUOC of Internal Medicine-Center of Hypertension and Nephrology Unit, Department of Systems Medicine, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.ORCID 0000-0001-8118-1330
Nicolò PiacentiniUOC of Internal Medicine-Center of Hypertension and Nephrology Unit, Department of Systems Medicine, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.
Leonarda GaliutoDepartment of Cardiovascular and Thoracic Sciences, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Università Cattolica del Sacro Cuore, Largo A. Gemelli 8, 00168 Rome, Italy.ORCID 0000-0002-6831-479X
Nicola Di DanieleUOC of Internal Medicine-Center of Hypertension and Nephrology Unit, Department of Systems Medicine, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.ORCID 0000-0001-7671-0015
Annalisa NoceUOC of Internal Medicine-Center of Hypertension and Nephrology Unit, Department of Systems Medicine, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy.ORCID 0000-0003-1310-3730
Foro Italico University of Rome · ITUniversity of Rome Tor Vergata · ITUniversità Cattolica del Sacro Cuore · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic kidney disease (CKD) is a clinical condition characterized by the loss of kidney function over time, as well as several complications affecting gastrointestinal, cardiovascular, and musculoskeletal systems. Physical exercise seems to induce positive adaptations in CKD patients, without side effects. Usually, these patients show a reduced physical activity and physical performance. The aim of this case-report was to evaluate the effects of an online training protocol on functional capacity and on muscle mass, in CKD stage III patients. Methods: Two CKD (stage III according to KDIGO guidelines) participants (1 female, Patient A; 1 male, Patient B) were enrolled and they performed an online tailored-supervised combined training lasting 12 weeks, including multi-joint strength exercises using TheraBand and an aerobic session at 65-70% of the patients' heart rate reserve. Results: Both patients showed an improving trend on functional capacity (6 min walking test: Patient A = +3%; Patient B = +5.3%) and on strength of the upper arms (handgrip strength test-right: Patient A = +13.4%; Patient B = +19.1%; handgrip strength test-left: Patient A = +42.8%; Patient B= +12.9%), as well as a reduction in inflammation and oxidative stress biomarkers. The protocol was feasible, and no side effects were evidenced. These case studies suggest that the online combined training can produce beneficial effects in CKD patients under conservative therapy, by reducing the CKD-related complications and improving the adherence to exercise of this population of patients, overcoming logistic barriers such as transportation, availability of facilities, and working and personal-life schedule.

Indexed as

chronic kidney diseasecombined trainingfunctional capacityonline training protocoloxidative stress

Identifiers

PMID35327050
PMCPMC8951501
OpenAlexW4221114049

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.