Evidence map›Paper›PMID 35327010›Full record

ArticleHealthcare (Basel, Switzerland)2022

Low-Pressure Laparoscopy Using the AirSeal System versus Standard Insufflation in Early-Stage Endometrial Cancer: A Multicenter, Retrospective Study (ARIEL Study).

Alessandro Buda, Giampaolo Di Martino, Martina Borghese, Stefano Restaino, Alessandra Surace, Andrea Puppo, Sara Paracchini, Debora Ferrari, Stefania Perotto, Antonia Novelli and 4 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Healthcare (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06737068 (Low Pressure Pneumoperitoneum Using AirSeal® for Reduction in Postoperative Shoulder Pain Following Robot Assisted Hiatal Hernia Repair), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06737068 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Low Pressure Pneumoperitoneum Using AirSeal® for Reduction in Postoperative Shoulder Pain Following Robot Assisted Hiatal Hernia Repair: a Prospective Randomized Controlled Trial.

TypeinterventionalSponsorRiverside University Health System Medical CenterRan2025 to 2027Enrolled120ConditionsHernia, Hiatal, Pneumoperitoneum, Postoperative Pain, Shoulder PainArmsLow pressure pneumoperitoneum (8-10mmHg) with AirSeal device, Standard pressure pneumoperitoneum (13- 15 mmHg) with AirSeal device
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 1 country.

Alessandro BudaDivision of Gynecologic Oncology, Michele e Pietro Ferrero Hospital, 12060 Verduno, Italy.
Giampaolo Di MartinoClinic of Gynecology and Obstetrics, San Gerardo Hospital, University of Milano-Bicocca, 20900 Monza, Italy.
Martina BorgheseClinic of Obstetrics and Gynecology, Santa Croce e Carle Hospital, 12100 Cuneo, Italy.
Stefano RestainoDivision of Obstetrics and Gynecology, University Hospital of Udine, Azienda Sanitaria Universitaria Friuli Centrale, 33100 Udine, Italy.ORCID 0000-0002-7848-0329
Alessandra SuraceDivision of Gynecologic Oncology, Michele e Pietro Ferrero Hospital, 12060 Verduno, Italy.ORCID 0000-0002-6937-1550
Andrea PuppoClinic of Obstetrics and Gynecology, Santa Croce e Carle Hospital, 12100 Cuneo, Italy.ORCID 0000-0003-1714-7765
Sara ParacchiniDivision of Gynecologic Oncology, Michele e Pietro Ferrero Hospital, 12060 Verduno, Italy.
Debora FerrariClinic of Gynecology and Obstetrics, San Gerardo Hospital, University of Milano-Bicocca, 20900 Monza, Italy.ORCID 0000-0001-7612-6847
Stefania PerottoDivision of Gynecologic Oncology, Michele e Pietro Ferrero Hospital, 12060 Verduno, Italy.
Antonia NovelliClinic of Obstetrics and Gynecology, Santa Croce e Carle Hospital, 12100 Cuneo, Italy.
Elena De PontiDivision of Medical Physics, ASST Monza, San Gerardo Hospital, University of Milan-Bicocca, 33100 Monza, Italy.ORCID 0000-0001-7035-6334
Chiara BorghiDivision of Gynecologic Oncology, Michele e Pietro Ferrero Hospital, 12060 Verduno, Italy.ORCID 0000-0001-5173-2285
Francesco FanfaniDipartimento della Salute della Donna, del Bambino e di Sanità Pubblica, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.
Robert FruscioClinic of Gynecology and Obstetrics, San Gerardo Hospital, University of Milano-Bicocca, 20900 Monza, Italy.ORCID 0000-0001-5688-2194
Ospedale San Pietro Fatebenefratelli · ITUniversity of Milano-Bicocca · ITAzienda Sanitaria Ospedaliera S.Croce e Carle Cuneo · ITOspedale Santa Maria della Misericordia di Udine · ITUniversità Cattolica del Sacro Cuore · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of our study was to evaluate the benefits of a low-pressure insufflation system (AirSeal) vs. a standard insufflation system in terms of anesthesiologists’ parameters and postoperative pain in patients undergoing laparoscopic surgery for early-stage endometrial cancer. This retrospective study involved five tertiary centers and included 152 patients with apparent early-stage disease who underwent laparoscopic surgical staging with either the low-pressure AirSeal system (8−10 mmHg, n = 84) or standard laparoscopic insufflation (10−12 mmHg, n = 68). All the intraoperative anesthesia variables evaluated (systolic blood pressure, end-tidal CO2, peak airway pressure) were significantly lower in the AirSeal group. We recorded a statistically significant difference between the two groups in the median NRS scores for global pain recorded at 4, 8, and 24 h, and for overall shoulder pain after surgery. Significantly more women in the AirSeal group were also discharged on day one compared to the standard group. All such results were confirmed when analyzing the subgroup of women with a BMI >30 kg/m2. In conclusion, according to our preliminary study, low-pressure laparoscopy represents a valid alternative to standard laparoscopy and could facilitate the development of outpatient surgery.

Indexed as

endometrial cancerlaparoscopylow-pressure insufflationpostoperative pain

Identifiers

PMID35327010
PMCPMC8953067
OpenAlexW4221067481

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.