Evidence map›Paper›PMID 35326845›Full record

ArticleAntibiotics (Basel, Switzerland)2022

Antimicrobial Prophylaxis in Neonates and Children Undergoing Dental, Maxillo-Facial or Ear-Nose-Throat (ENT) Surgery: A RAND/UCLA Appropriateness Method Consensus Study.

Erika Rigotti, Sonia Bianchini, Laura Nicoletti, Sara Monaco, Elena Carrara, Francesca Opri, Roberta Opri, Caterina Caminiti, Daniele Donà, Mario Giuffré and 13 more

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 11 institutions in 1 country.

Erika RigottiPediatric Unit, Department of Surgical Sciences, Dentistry, Gynecology and Pediatrics, University of Verona, 37124 Verona, Italy.
Sonia BianchiniPediatric Clinic, University Hospital, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy.
Laura NicolettiPediatric Clinic, University Hospital, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy.
Sara MonacoPediatric Clinic, University Hospital, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy.
Elena CarraraInfectious Diseases Section, Department of Diagnostics and Public Health, University of Verona, 37134 Verona, Italy.
Francesca OpriPediatric Unit, Department of Surgical Sciences, Dentistry, Gynecology and Pediatrics, University of Verona, 37124 Verona, Italy.ORCID 0000-0001-6073-1348
Roberta OpriPediatric Unit, Department of Surgical Sciences, Dentistry, Gynecology and Pediatrics, University of Verona, 37124 Verona, Italy.ORCID 0000-0001-5660-3992
Caterina CaminitiResearch and Innovation Unit, University Hospital of Parma, 43126 Parma, Italy.ORCID 0000-0002-3196-2435
Daniele DonàDivision of Paediatric Infectious Diseases, Department for Woman and Child Health, University of Padua, 35100 Padua, Italy.
Mario GiuffréDepartment of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties "G. D'Alessandro", University of Palermo, 90134 Palermo, Italy.ORCID 0000-0001-9576-1635
Alessandro InserraGeneral Surgery Department, Bambino Gesu Children's Hospital, Istituto di Ricerca e Cura a Carattere Scientifico (IRCCS), 00165 Rome, Italy.ORCID 0000-0002-5663-8674
Laura LancellaPaediatric and Infectious Disease Unit, Academic Department of Pediatrics, IRCCS Bambino Gesù Children's Hospital, 00165 Rome, Italy.
Alessandro MugelliDepartment of Neurosciences, Psychology, Drug Research and Child Health, Section of Pharmacology and Toxicology, University of Florence, Viale G. Pieraccini, 6, 50139 Florence, Italy.
Giorgio PiacentiniPediatric Unit, Department of Surgical Sciences, Dentistry, Gynecology and Pediatrics, University of Verona, 37124 Verona, Italy.
Nicola PrincipiUniversità degli Studi di Milano, 20122 Milan, Italy.ORCID 0000-0002-3468-5568
Simonetta TesoroDivision of Anesthesia, Analgesia, and Intensive Care, Department of Surgical and Biomedical Sciences, University of Perugia, 06129 Perugia, Italy.
Elisabetta VenturiniPediatric Infectious Disease Unit, Meyer Children's Hospital, 50139 Florence, Italy.ORCID 0000-0002-0048-3933
Annamaria StaianoDepartment of Translational Medical Science, Section of Pediatrics, University of Naples "Federico II", 80138 Naples, Italy.
Alberto VillaniPaediatric and Infectious Disease Unit, Academic Department of Pediatrics, IRCCS Bambino Gesù Children's Hospital, 00165 Rome, Italy.ORCID 0000-0002-9120-0424
Enrico SesennaMaxillo-Facial Surgery Unit, Head and Neck Department, University Hospital of Parma, 43126 Parma, Italy.
Claudio ViciniHead-Neck and Oral Surgery Unit, Department of Head-Neck Surgery, Otolaryngology, Morgagni Piertoni Hospital, 47121 Forli, Italy.
Susanna EspositoPediatric Clinic, University Hospital, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy.
On Behalf Of The Peri-Operative Prophylaxis In Neonatal And Paediatric Age Pop-NeoPed Study Group
University of Parma · ITUniversity of Verona · ITBambino Gesù Children's Hospital · ITMeyer Children's Hospital · ITOspedale G.B. Morgagni - L.Pierantoni · ITUniversity of Florence · ITUniversity of Milan · ITUniversity of Naples Federico II · ITUniversity of Padua · ITUniversity of Palermo · ITUniversity of Perugia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Surgical site infections (SSIs) represent a potential complication in surgical procedures, mainly because clean/contaminated surgery involves organs that are normally colonized by bacteria. Dental, maxillo-facial and ear-nose-throat (ENT) surgeries are among those that carry a risk of SSIs because the mouth and the first respiratory tracts are normally colonized by a bacterial flora. The aim of this consensus document was to provide clinicians with recommendations on surgical antimicrobial prophylaxis in neonates (<28 days of chronological age) and pediatric patients (within the age range of 29 days−18 years) undergoing dental, maxillo-facial or ENT surgical procedures. These included: (1) dental surgery; (2) maxilla-facial surgery following trauma with fracture; (3) temporo-mandibular surgery; (4) cleft palate and cleft lip repair; (5) ear surgery; (6) endoscopic paranasal cavity surgery and septoplasty; (7) clean head and neck surgery; (8) clean/contaminated head and neck surgery and (9) tonsillectomy and adenoidectomy. Due to the lack of pediatric data for the majority of dental, maxillo-facial and ENT surgeries and the fact that the recommendations for adults are currently used, there is a need for ad hoc studies to be rapidly planned for the most deficient areas. This seems even more urgent for interventions such as those involving the first airways since the different composition of the respiratory microbiota in children compared to adults implies the possibility that surgical antibiotic prophylaxis schemes that are ideal for adults may not be equally effective in children.

Indexed as

dental surgeryENT surgeryhead and neck surgerymaxilla-facial surgerysurgical antimicrobial prophylaxis

Identifiers

PMID35326845
PMCPMC8944694
OpenAlexW4220969813

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.